PDF(Pubmed)
Abstract：
The primary aim was to predict upper airway collapse sites found in drug-induced sleep endoscopy (DISE) from demographic, anthropometric, clinical examination, sleep study, and snoring sound parameters in patients with obstructive sleep apnea (OSA). The secondary aim was to identify the above-mentioned parameters that are associated with complete concentric collapse of the soft palate.
All patients with OSA who underwent DISE and simultaneous snoring sound recording were enrolled in this study. Demographic, anthropometric, clinical examination (viz., modified Mallampati classification and Friedman tonsil classification), and sleep study parameters were extracted from the polysomnography and DISE reports. Snoring sound parameters during DISE were calculated.
One hundred and nineteen patients with OSA (79.8% men; age = 48.1 ± 12.4 years) were included. Increased body mass index was found to be associated with higher probability of oropharyngeal collapse (P < .01; odds ratio = 1.29). Patients with a high Friedman tonsil score were less likely to have tongue base collapse (P < .01; odd ratio = 0.12) and epiglottic collapse (P = .01; odds ratio = 0.20) than those with a low score. A longer duration of snoring events (P = .05; odds ratio = 2.99) was associated with a higher probability of complete concentric collapse of the soft palate.
Within the current patient profile and approach, given that only a limited number of predictors were identified, it does not seem feasible to predict upper airway collapse sites found in DISE from demographic, anthropometric, clinical examination, sleep study, and snoring sound parameters in patients with OSA.
Huang Z, Bosschieter PFN, Aarab G, et al. Predicting upper airway collapse sites found in drug-induced sleep endoscopy from clinical data and snoring sounds in obstructive sleep apnea patients: a prospective clinical study. J Clin Sleep Med. 2022;18(9):2119-2131.
All patients with OSA who underwent DISE and simultaneous snoring sound recording were enrolled in this study. Demographic, anthropometric, clinical examination (viz., modified Mallampati classification and Friedman tonsil classification), and sleep study parameters were extracted from the polysomnography and DISE reports. Snoring sound parameters during DISE were calculated.
One hundred and nineteen patients with OSA (79.8% men; age = 48.1 ± 12.4 years) were included. Increased body mass index was found to be associated with higher probability of oropharyngeal collapse (P < .01; odds ratio = 1.29). Patients with a high Friedman tonsil score were less likely to have tongue base collapse (P < .01; odd ratio = 0.12) and epiglottic collapse (P = .01; odds ratio = 0.20) than those with a low score. A longer duration of snoring events (P = .05; odds ratio = 2.99) was associated with a higher probability of complete concentric collapse of the soft palate.
Within the current patient profile and approach, given that only a limited number of predictors were identified, it does not seem feasible to predict upper airway collapse sites found in DISE from demographic, anthropometric, clinical examination, sleep study, and snoring sound parameters in patients with OSA.
Huang Z, Bosschieter PFN, Aarab G, et al. Predicting upper airway collapse sites found in drug-induced sleep endoscopy from clinical data and snoring sounds in obstructive sleep apnea patients: a prospective clinical study. J Clin Sleep Med. 2022;18(9):2119-2131.
摘要：
主要目的是从人口统计学预测药物诱导的睡眠内窥镜检查（DISE）中发现的上呼吸道塌陷部位。人体测量学,临床检查,睡眠研究,阻塞性睡眠呼吸暂停（OSA）患者的打鼾声音参数。次要目的是确定与软腭完全同心塌陷相关的上述参数。
本研究纳入所有接受DISE和同时打鼾录音的OSA患者。人口统计,人体测量学,临床检查(即,改良的Mallampati分类法和弗里德曼扁桃体分类法)，和睡眠研究参数从多导睡眠图和DISE报告中提取。计算DISE期间的打鼾声音参数。
纳入了119例OSA患者（男性占79.8％；年龄=48.1±12.4岁）。发现体重指数增加与口咽塌陷的可能性更高相关（P<.01；比值比=1.29）。Friedman扁桃体评分高的患者与评分低的患者相比，舌根塌陷（P<.01；奇数比=0.12）和会厌塌陷（P=.01；比值比=0.20）的可能性较小。打鼾事件持续时间较长（P=0.05；比值比=2.99）与软腭完全同心塌陷的可能性较高有关。
在当前的患者概况和方法中，鉴于只确定了有限数量的预测因子，从人口统计中预测DISE中发现的上呼吸道塌陷部位似乎不可行，人体测量学,临床检查,睡眠研究,OSA患者的打鼾声音参数。
黄Z,BoschieterPFN,AarabG,etal.从阻塞性睡眠呼吸暂停患者的临床数据和打鼾声音预测药物诱导睡眠内窥镜检查中发现的上呼吸道塌陷部位：一项前瞻性临床研究。JClinSleepMed.2022年；18（9）：2119-2131。
本研究纳入所有接受DISE和同时打鼾录音的OSA患者。人口统计,人体测量学,临床检查(即,改良的Mallampati分类法和弗里德曼扁桃体分类法)，和睡眠研究参数从多导睡眠图和DISE报告中提取。计算DISE期间的打鼾声音参数。
纳入了119例OSA患者（男性占79.8％；年龄=48.1±12.4岁）。发现体重指数增加与口咽塌陷的可能性更高相关（P<.01；比值比=1.29）。Friedman扁桃体评分高的患者与评分低的患者相比，舌根塌陷（P<.01；奇数比=0.12）和会厌塌陷（P=.01；比值比=0.20）的可能性较小。打鼾事件持续时间较长（P=0.05；比值比=2.99）与软腭完全同心塌陷的可能性较高有关。
在当前的患者概况和方法中，鉴于只确定了有限数量的预测因子，从人口统计中预测DISE中发现的上呼吸道塌陷部位似乎不可行，人体测量学,临床检查,睡眠研究,OSA患者的打鼾声音参数。
黄Z,BoschieterPFN,AarabG,etal.从阻塞性睡眠呼吸暂停患者的临床数据和打鼾声音预测药物诱导睡眠内窥镜检查中发现的上呼吸道塌陷部位：一项前瞻性临床研究。JClinSleepMed.2022年；18（9）：2119-2131。
