PDF(Pubmed)
Abstract：
The pandemic of the coronavirus disease 2019 (COVID-19) has made biotextiles, including face masks and protective clothing, quite familiar in our daily lives. Biotextiles are one broad category of textile products that are beyond our imagination. Currently, biotextiles have been routinely utilized in various biomedical fields, like daily protection, wound healing, tissue regeneration, drug delivery, and sensing, to improve the health and medical conditions of individuals. However, these biotextiles are commonly manufactured with fibers with diameters on the micrometer scale (> 10 μm). Recently, nanofibrous materials have aroused extensive attention in the fields of fiber science and textile engineering because the fibers with nanoscale diameters exhibited obviously superior performances, such as size and surface/interface effects as well as optical, electrical, mechanical, and biological properties, compared to microfibers. A combination of innovative electrospinning techniques and traditional textile-forming strategies opens a new window for the generation of nanofibrous biotextiles to renew and update traditional microfibrous biotextiles. In the last two decades, the conventional electrospinning device has been widely modified to generate nanofiber yarns (NYs) with the fiber diameters less than 1000 nm. The electrospun NYs can be further employed as the primary processing unit for manufacturing a new generation of nano-textiles using various textile-forming strategies. In this review, starting from the basic information of conventional electrospinning techniques, we summarize the innovative electrospinning strategies for NY fabrication and critically discuss their advantages and limitations. This review further covers the progress in the construction of electrospun NY-based nanotextiles and their recent applications in biomedical fields, mainly including surgical sutures, various scaffolds and implants for tissue engineering, smart wearable bioelectronics, and their current and potential applications in the COVID-19 pandemic. At the end, this review highlights and identifies the future needs and opportunities of electrospun NYs and NY-based nanotextiles for clinical use.
摘要：
2019年冠状病毒病（COVID-19）的大流行使生物织物，包括口罩和防护服，在我们的日常生活中非常熟悉。生物织物是超出我们想象的一类广泛的纺织品。目前,生物织物已被常规用于各种生物医学领域，比如日常保护，伤口愈合，组织再生，药物输送,和感应，改善个人的健康和医疗条件。然而,这些生物织物通常用直径为微米级(>10μm)的纤维制造。最近,纳米纤维材料由于纳米直径的纤维表现出明显优越的性能,在纤维科学和纺织工程领域引起了广泛的关注,如尺寸和表面/界面效应以及光学，电气,机械,和生物学特性，与微纤维相比。创新的静电纺丝技术和传统的纺织品成型策略的结合为纳米纤维生物织物的产生打开了新的窗口，以更新和更新传统的微纤维生物织物。在过去的二十年里，传统的静电纺丝装置已经被广泛地改进以产生纤维直径小于1000nm的纳米纤维纱线(NYs)。电纺NYs可以进一步用作主要加工单元,用于使用各种纺织品形成策略制造新一代纳米纺织品。在这次审查中,从常规静电纺丝技术的基本信息开始，我们总结了用于NY制造的创新静电纺丝策略，并批判性地讨论了它们的优势和局限性。这篇综述进一步涵盖了基于NY的静电纺丝纳米织物的构建进展及其在生物医学领域的最新应用。主要包括外科缝合，用于组织工程的各种支架和植入物，智能可穿戴生物电子学，以及它们在COVID-19大流行中的当前和潜在应用。最后,这篇综述强调并确定了用于临床的静电纺丝NYs和基于NY的纳米织物的未来需求和机会.
