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Abstract：
BACKGROUND: Post-inflammatory erythema (PIE) and post-inflammatory hyperpigmentation (PIH) are the most common acne-related sequelae with no effective treatments. By combining different cut-off filters, intense pulsed light (IPL) therapy can effectively treat these conditions with few side effects. While the safety and effectiveness of IPL for treating post-burn hyperpigmentation is well known, there is little evidence for its benefits for acne-related PIH. In this article, we evaluate the efficacy and safety of IPL for the treatment of acne-related PIE and PIH.
METHODS: This retrospective study evaluated 60 patients with more than 6 months of PIE and PIH treated by the same IPL device and similar protocols. The treatment included three to seven sessions at 4-6-week intervals, and three cut-off filters (640 nm, 590 nm and 560 nm) were used sequentially in each session. Using the Global Aesthetic Improvement Scale (GAIS), Cardiff Acne Disability Index (CADI), and Erythema Assessment Scale (EAS), patients were evaluated on the basis of their facial photographs. The facial brown spots and red areas were visualised and analysed using the VISIA-CR system. Six months after the last treatment, the patients were assessed for acne relapse or any side effects.Please check and confirm that the authors and their respective affiliations have been correctly processed and amend if necessary.Checked and confirmed. No further corrections.
RESULTS: On the basis of the GAIS, 49 of 60 patients (81.7%) showed complete or partial clearance of erythema and hyperpigmentation. The CADI and EAS scores showed significant improvement (p < 0.01) after IPL treatment compared with pre-treatment. A significant reduction (p < 0.01) in the facial brown spots and red areas was seen after IPL treatment. While no long-term side effects were reported, seven patients (11.7%) experienced acne relapse at follow-up.
CONCLUSIONS: IPL is an effective and safe treatment for acne-related PIE and PIH.
METHODS: This retrospective study evaluated 60 patients with more than 6 months of PIE and PIH treated by the same IPL device and similar protocols. The treatment included three to seven sessions at 4-6-week intervals, and three cut-off filters (640 nm, 590 nm and 560 nm) were used sequentially in each session. Using the Global Aesthetic Improvement Scale (GAIS), Cardiff Acne Disability Index (CADI), and Erythema Assessment Scale (EAS), patients were evaluated on the basis of their facial photographs. The facial brown spots and red areas were visualised and analysed using the VISIA-CR system. Six months after the last treatment, the patients were assessed for acne relapse or any side effects.Please check and confirm that the authors and their respective affiliations have been correctly processed and amend if necessary.Checked and confirmed. No further corrections.
RESULTS: On the basis of the GAIS, 49 of 60 patients (81.7%) showed complete or partial clearance of erythema and hyperpigmentation. The CADI and EAS scores showed significant improvement (p < 0.01) after IPL treatment compared with pre-treatment. A significant reduction (p < 0.01) in the facial brown spots and red areas was seen after IPL treatment. While no long-term side effects were reported, seven patients (11.7%) experienced acne relapse at follow-up.
CONCLUSIONS: IPL is an effective and safe treatment for acne-related PIE and PIH.
摘要：
背景：炎症后红斑（PIE）和炎症后色素沉着过度（PIH）是最常见的痤疮相关后遗症，没有有效的治疗方法。通过组合不同的截止滤波器，强脉冲光（IPL）疗法可以有效治疗这些疾病，副作用少。虽然IPL治疗烧伤后色素沉着的安全性和有效性是众所周知的，几乎没有证据表明其对痤疮相关的PIH的益处。在这篇文章中,我们评估了IPL治疗痤疮相关PIE和PIH的有效性和安全性。
方法：这项回顾性研究评估了60例接受相同IPL装置和类似方案治疗的PIE和PIH超过6个月的患者。治疗包括三到七个疗程，间隔4-6周，和三个截止滤波器（640nm，在每个阶段中依次使用590nm和560nm）。使用全球美学改善量表(GAIS)，卡迪夫痤疮残疾指数（CADI），和红斑评估量表(EAS)，根据患者的面部照片对患者进行评估.使用VISIA-CR系统对面部褐色斑点和红色区域进行可视化和分析。最后一次治疗六个月后，评估患者的痤疮复发或任何副作用.请检查并确认作者及其各自的从属关系已被正确处理，并在必要时进行修改。检查并确认。没有进一步的更正。
结果：在GAIS的基础上，60例患者中有49例（81.7％）显示完全或部分清除红斑和色素沉着。与治疗前相比，IPL治疗后CADI和EAS评分显着改善（p<0.01）。在IPL处理后观察到面部棕色斑点和红色区域的显著减少(p<0.01)。虽然没有长期副作用的报道，7例患者(11.7%)在随访时出现痤疮复发.
结论：IPL是治疗痤疮相关PIE和PIH的有效和安全的方法。
方法：这项回顾性研究评估了60例接受相同IPL装置和类似方案治疗的PIE和PIH超过6个月的患者。治疗包括三到七个疗程，间隔4-6周，和三个截止滤波器（640nm，在每个阶段中依次使用590nm和560nm）。使用全球美学改善量表(GAIS)，卡迪夫痤疮残疾指数（CADI），和红斑评估量表(EAS)，根据患者的面部照片对患者进行评估.使用VISIA-CR系统对面部褐色斑点和红色区域进行可视化和分析。最后一次治疗六个月后，评估患者的痤疮复发或任何副作用.请检查并确认作者及其各自的从属关系已被正确处理，并在必要时进行修改。检查并确认。没有进一步的更正。
结果：在GAIS的基础上，60例患者中有49例（81.7％）显示完全或部分清除红斑和色素沉着。与治疗前相比，IPL治疗后CADI和EAS评分显着改善（p<0.01）。在IPL处理后观察到面部棕色斑点和红色区域的显著减少(p<0.01)。虽然没有长期副作用的报道，7例患者(11.7%)在随访时出现痤疮复发.
结论：IPL是治疗痤疮相关PIE和PIH的有效和安全的方法。
