关键词: Sarcopenia local recurrence malignant bone postoperative complications soft tissue tumor wide resection

来  源:   DOI:10.21873/cdp.10094   PDF(Pubmed)

Abstract:
UNASSIGNED: We determined the impact of sarcopenia on the treatment outcomes of malignant bone and soft tissue tumors in elderly patients.
UNASSIGNED: We retrospectively reviewed 76 patients (age ≥65 years) who were treated for malignant bone and soft tissue tumors. Sarcopenia was assessed by measuring the cross-sectional area of the psoas muscles at the L3 vertebra from preoperative computed tomography images and categorized using the total psoas area/m 2 (TPA/m 2 ) ≤5.0 cm 2 /m 2 . The patients\' clinical data were then evaluated.
UNASSIGNED: The operation time, length of hospital stay, and median overall survival were not different between the sarcopenia (n=41) and no-sarcopenia (n=35) groups. The local recurrence rate (p=0.01) and incidence of postoperative complications (p=0.02) significantly differed between both groups. The TPA/m 2  of both groups significantly decreased at the final follow-up.
UNASSIGNED: Sarcopenia negatively influenced wound healing and local recurrence, and was significantly exacerbated postoperatively in all elderly patients.
摘要:
UNASSIGNED:我们确定了少肌症对老年患者恶性骨和软组织肿瘤治疗结果的影响。
UNASSIGNED:我们回顾性分析了76例因恶性骨和软组织肿瘤接受治疗的患者(年龄≥65岁)。通过从术前计算机断层扫描图像测量L3椎骨的腰大肌的横截面积来评估肌肉减少症,并使用总腰大肌面积/m2(TPA/m2)≤5.0cm2/m2进行分类。然后评估患者的临床数据。
UNASSIGNED:操作时间,住院时间,肌少症组(n=41)和非肌少症组(n=35)的中位总生存期无差异.两组的局部复发率(p=0.01)和术后并发症发生率(p=0.02)显着不同。两组的TPA/m2在最终随访时均显着降低。
未经证实:肌肉减少对伤口愈合和局部复发有负面影响,所有老年患者术后均明显加重。
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