关键词: Azadirachta indica Herbal Morinda citrifolia Triphala endodontic irrigants Azadirachta indica Herbal Morinda citrifolia Triphala endodontic irrigants

来  源:   DOI:10.4103/ayu.AYU_102_20   PDF(Pubmed)

Abstract:
UNASSIGNED: The success of the root canal treatment depends on the complete elimination of the microflora, biofilms and smear layer from the pulp space. A wide variety of chemical endodontic irrigants are available to achieve disinfection and thorough debridement besides mechanical means. However, detrimental properties such as allergic potential, cytotoxicity, antimicrobial resistance and safety concerns have intrigued researchers over the years to look for safer options.
UNASSIGNED: The review is aimed at providing comprehensive information of the studies evaluating the efficacy of Azadirachta indica A. juss (A. indica), Morinda citrifolia L. (M. citrifolia) and Triphala (fruits of Emblica officinalis Gaertn., Terminalia chebula (Gaertn.) Roxb. and Terminalia belerica Retz.) as herbal endodontic irrigants.
UNASSIGNED: The literature review was conducted using indexed databases (PubMed, Google Scholar, Cochrane) electronically for publications in peer-reviewed journals for relevant articles evaluating the efficacy of A. indica, Triphala, M. citrifolia as endodontic irrigant from the year 1985-March 2020.
UNASSIGNED: A total of 58 studies were identified for full text reviewing after duplicate removal and screening title and abstracts. A total of 32 studies were included and processed for data extractions.
UNASSIGNED: Various in-vitro/in-vivo studies utilizing these herbal irrigants have documented promising results and hold the potential to replace chemical endodontic irrigants in routine practice but more preclinical and clinical trials are needed to substantiate these results before they can conclusively be recommended as intracanal irrigating solutions.
摘要:
UNASSIGNED:根管治疗的成功取决于完全消除微生物区系,来自纸浆空间的生物膜和涂抹层。除机械手段外,还有各种各样的化学牙髓冲洗剂可用于实现消毒和彻底清创。然而,有害特性,如过敏潜力,细胞毒性,多年来,抗菌素耐药性和安全性问题引起了研究人员的兴趣,以寻找更安全的选择。
UNASSIGNED:该综述旨在提供有关评估AzadirachtaA.juss疗效的研究的全面信息(A.印度),巴林达(M.citrifolia)和Triphala(EmblicaofficinalisGaertn的果实。,Terminaliachebula(Gaertn.)Roxb。和TerminaliaBelericaRetz.)作为草药牙髓灌溉剂。
UNASSIGNED:文献综述是使用索引数据库(PubMed,谷歌学者,Cochrane)以电子方式在同行评审的期刊上发表有关评估A.indica疗效的相关文章,Triphala,从1985年至2020年3月作为牙髓冲洗剂。
UNASSIGNED:在删除重复和筛选标题和摘要后,共确定了58项研究用于全文审查。共有32项研究被纳入并处理数据提取。
UNASSIGNED:利用这些草药冲洗剂的各种体外/体内研究已经证明了有希望的结果,并且在常规实践中具有替代化学牙髓冲洗剂的潜力,但是需要更多的临床前和临床试验来证实这些结果,然后才能最终推荐它们作为肛内冲洗溶液。
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