关键词: craniofacial deformity experimental model neurological disorders zebrafish craniofacial deformity experimental model neurological disorders zebrafish

来  源:   DOI:10.14202/vetworld.2022.22-29   PDF(Pubmed)

Abstract:
Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are very expensive, it is necessary to develop affordable and valid experimental models. This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity.
摘要:
近年来,斑马鱼已成为领先的实验模型。目前,斑马鱼脊椎动物模型由于其与人类的多因素相似性而越来越多地使用,包括遗传,器官,和细胞因子。随着昂贵的新研究技术的出现,有必要开发负担得起的有效实验模型。这篇评论旨在强调斑马鱼与人类之间最重要的相似之处,强调第一个在模拟神经系统疾病和颅面畸形方面的相关性。
公众号