关键词: Gaps Gynecology Prioritization Randomized controlled trials Research waste Systematic reviews

来  源:   DOI:10.1016/j.jclinepi.2022.03.020

Abstract:
OBJECTIVE: The aim of this project was to identify gaps and research waste in the dissemination of gynecology evidence in Cochrane systematic reviews (CSRs).
METHODS: A cross-sectional study of the Cochrane Gynecology and Fertility (CGF) Group\'s specialized register of randomized controlled trials (RCTs). We included trials on benign gynecological conditions, published in 2010 and 2011. These trials were matched, by the condition and treatment, to existing Cochrane reviews. Unmatched trials were analysed to prioritize new review titles.
RESULTS: After exporting 740 trials from the CGF specialized register, we found that 192 (26%) could be included in an existing CSR if it was updated, whereas 230 trials (32%) were not matched to any review title, and from these, we developed 21 new review titles. The topic with the largest number of associated \'unused\' trials was \'Plant and herbal extracts for symptoms of menopause\'.
CONCLUSIONS: We found that a third of the benign gynecology trials published in 2010 and 2011 had no associated CSR. After identifying new topics from unmatched trials, we developed new CSR titles. This study identified the gaps in the evidence for women with gynecological problems.
摘要:
目的:该项目的目的是在Cochrane系统评价(CSR)中发现妇科证据传播方面的差距和研究浪费。
方法:一项关于Cochrane妇科和生育(CGF)组专门注册的随机对照试验(RCT)的横断面研究。我们纳入了良性妇科疾病的试验,发表于2010年和2011年。这些试验是匹配的,根据病情和治疗,现有的Cochrane评论。分析了未匹配的试验,以优先考虑新的评论标题。
结果:从CGF专业注册中心导出740项试验后,我们发现,如果更新了现有的CSR,则可以将192(26%)包括在现有的CSR中,而230项试验(32%)与任何评论标题不匹配,从这些,我们开发了21个新的评论标题。相关的“未使用”试验数量最多的主题是“用于更年期症状的植物和草药提取物”。
结论:我们发现,在2010年和2011年发表的良性妇科试验中,有三分之一没有相关的CSR。在从无与伦比的试验中确定新主题后,我们开发了新的CSR头衔。这项研究确定了女性妇科问题的证据差距。
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