PDF(Pubmed)
Abstract：
Characterizing RNA structures and functions have mostly been focused on 2D, secondary and 3D, tertiary structures. Recent advances in experimental and computational techniques for probing or predicting RNA solvent accessibility make this 1D representation of tertiary structures an increasingly attractive feature to explore. Here, we provide a survey of these recent developments, which indicate the emergence of solvent accessibility as a simple 1D property, adding to secondary and tertiary structures for investigating complex structure-function relations of RNAs.
摘要：
表征RNA结构和功能主要集中在2D上，次级和3D，三级结构。用于探测或预测RNA溶剂可及性的实验和计算技术的最新进展使这种三级结构的1D表示成为越来越有吸引力的探索特征。这里,我们提供了对这些最新发展的调查，这表明溶剂可及性的出现是一个简单的一维属性，添加二级和三级结构以研究RNA的复杂结构-功能关系。
