PDF(Pubmed)
Abstract：
UNASSIGNED: There are >1 million emergency department visits and 100,000 admissions with urinary tract infection (UTI) annually in the United States. A fraction of total UTI volume, complicated (cUTI) costs the health care system over $3.5 billion per year. We evaluated the contemporary annual burden of emergency department (ED) visits with cUTI.
UNASSIGNED: We conducted a cross-sectional multicenter study within the National Emergency Department database, a 20% stratified sample of all US hospital-based EDs, 2016-2018, to explore characteristics of visits with a cUTI. We compared cUTI as the principal (PD) versus secondary diagnosis (non-PD). We applied survey methods to develop national estimates.
UNASSIGNED: Among 2,379,448 ED cUTI visits (44.8% PD), 40.1% were female (45.1% PD; 36.9% non-PD) and 62.2% were ≥ 65 years (52.5% PD; 70.2% non-PD). Mean Charlson score was 2.3 (3.0 PD; 2.1 non-PD); end-stage renal disease prevalence was 2.3% (1.4% PD; 3.0% non-PD). Whereas pyelonephritis occurred in ∼10% of both groups, severe sepsis (7.2% vs 2.0%) and septic shock (7.1% vs 1.8%) were ∼4 times more prevalent among those with cUTI-non-PD than cUTI-PD. Overall, two thirds of all visits ended in hospitalization (44.9% PD; 85.5% non-PD). Despite similar numbers of visits, the annual national ED bill for cUTI rose from $2.8 billion in 2016 to $3.2 billion in 2018.
UNASSIGNED: There were over 2 million ED visits with cUTI in 2016-2018. Although <10% met criteria for severe sepsis/septic shock, ∼two thirds were admitted. The aggregate cost for cUTI visits rose by 15% without a substantial increase in volume.
UNASSIGNED: We conducted a cross-sectional multicenter study within the National Emergency Department database, a 20% stratified sample of all US hospital-based EDs, 2016-2018, to explore characteristics of visits with a cUTI. We compared cUTI as the principal (PD) versus secondary diagnosis (non-PD). We applied survey methods to develop national estimates.
UNASSIGNED: Among 2,379,448 ED cUTI visits (44.8% PD), 40.1% were female (45.1% PD; 36.9% non-PD) and 62.2% were ≥ 65 years (52.5% PD; 70.2% non-PD). Mean Charlson score was 2.3 (3.0 PD; 2.1 non-PD); end-stage renal disease prevalence was 2.3% (1.4% PD; 3.0% non-PD). Whereas pyelonephritis occurred in ∼10% of both groups, severe sepsis (7.2% vs 2.0%) and septic shock (7.1% vs 1.8%) were ∼4 times more prevalent among those with cUTI-non-PD than cUTI-PD. Overall, two thirds of all visits ended in hospitalization (44.9% PD; 85.5% non-PD). Despite similar numbers of visits, the annual national ED bill for cUTI rose from $2.8 billion in 2016 to $3.2 billion in 2018.
UNASSIGNED: There were over 2 million ED visits with cUTI in 2016-2018. Although <10% met criteria for severe sepsis/septic shock, ∼two thirds were admitted. The aggregate cost for cUTI visits rose by 15% without a substantial increase in volume.
摘要：
未经评估：在美国，每年有>100万急诊就诊和100,000例尿路感染（UTI）入院。UTI总体积的一小部分，复杂(cUTI)每年给医疗保健系统带来超过35亿美元的成本。我们用cUTI评估了急诊室（ED）就诊的当代年度负担。
UNASSIGNED：我们在国家急诊室数据库中进行了一项横断面多中心研究，所有美国医院ED的20%分层抽样，2016-2018年，探索具有cUTI的访问特征。我们比较了cUTI作为主要诊断(PD)和次要诊断(非PD)。我们应用调查方法来制定国家估计。
未经批准：在2,379,448例EDcUTI访问（44.8％PD）中，40.1%为女性（45.1%PD；36.9%非PD），62.2%≥65岁（52.5%PD；70.2%非PD）。平均Charlson评分为2.3（3.0PD；2.1非PD）；终末期肾病患病率为2.3％（1.4％PD；3.0％非PD）。而肾盂肾炎发生在两组的10%，严重脓毒症(7.2%vs2.0%)和脓毒性休克(7.1%vs1.8%)在cUTI-non-PD患者中的发病率是cUTI-PD的4倍.总的来说,所有访视的三分之二以住院结束(44.9%PD;85.5%非PD).尽管访问次数相似，cUTI的年度全国ED账单从2016年的28亿美元上升到2018年的32亿美元。
未经评估：在2016-2018年，cUTI有超过200万次ED访问。尽管<10%符合严重脓毒症/脓毒性休克的标准，三分之二被录取。cUTI访问的总成本上升了15%，但数量没有大幅增加。
UNASSIGNED：我们在国家急诊室数据库中进行了一项横断面多中心研究，所有美国医院ED的20%分层抽样，2016-2018年，探索具有cUTI的访问特征。我们比较了cUTI作为主要诊断(PD)和次要诊断(非PD)。我们应用调查方法来制定国家估计。
未经批准：在2,379,448例EDcUTI访问（44.8％PD）中，40.1%为女性（45.1%PD；36.9%非PD），62.2%≥65岁（52.5%PD；70.2%非PD）。平均Charlson评分为2.3（3.0PD；2.1非PD）；终末期肾病患病率为2.3％（1.4％PD；3.0％非PD）。而肾盂肾炎发生在两组的10%，严重脓毒症(7.2%vs2.0%)和脓毒性休克(7.1%vs1.8%)在cUTI-non-PD患者中的发病率是cUTI-PD的4倍.总的来说,所有访视的三分之二以住院结束(44.9%PD;85.5%非PD).尽管访问次数相似，cUTI的年度全国ED账单从2016年的28亿美元上升到2018年的32亿美元。
未经评估：在2016-2018年，cUTI有超过200万次ED访问。尽管<10%符合严重脓毒症/脓毒性休克的标准，三分之二被录取。cUTI访问的总成本上升了15%，但数量没有大幅增加。
