Abstract：
Obesity is a well-known modified risk factor for isolated systolic hypertension (ISH), but evidence is lacking regarding whether the combination of anthropometric and lipid indicators could strengthen their correlation with ISH. Therefore, we compared the association of body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product index (LAP), and cardiometabolic index (CMI) with ISH.
A total of 106,248 adults who received routine health screening and did not have diastolic blood pressure ≥ 90 mmHg were recruited in this cross-sectional study. The associations between these indicators and ISH were evaluated using multivariate regression.
Each standard deviation (SD) increase in traditional obesity indicators (especially WHR and WHtR) had significantly higher multivariate-adjusted odds ratios (ORs) than each SD increase in lipid-related obesity indicators. In addition, multivariate-adjusted ORs for ISH in the third (vs. the first) tertile of traditional obesity indicators were also significantly higher than those of lipid-related indicators. Moreover, traditional obesity indicators exhibited a higher area under the ROC curve for discriminating ISH than lipid-related obesity indicators.
Traditional obesity indicators were more strongly associated with ISH than lipid-related obesity indicators among Chinese adults.
A total of 106,248 adults who received routine health screening and did not have diastolic blood pressure ≥ 90 mmHg were recruited in this cross-sectional study. The associations between these indicators and ISH were evaluated using multivariate regression.
Each standard deviation (SD) increase in traditional obesity indicators (especially WHR and WHtR) had significantly higher multivariate-adjusted odds ratios (ORs) than each SD increase in lipid-related obesity indicators. In addition, multivariate-adjusted ORs for ISH in the third (vs. the first) tertile of traditional obesity indicators were also significantly higher than those of lipid-related indicators. Moreover, traditional obesity indicators exhibited a higher area under the ROC curve for discriminating ISH than lipid-related obesity indicators.
Traditional obesity indicators were more strongly associated with ISH than lipid-related obesity indicators among Chinese adults.
摘要：
肥胖是众所周知的单纯性收缩期高血压（ISH）的改良危险因素，但是缺乏关于人体测量和血脂指标的组合是否可以增强其与ISH的相关性的证据。因此,我们比较了身体质量指数(BMI)，腰围（WC），腰臀比（WHR），腰围与身高比(WHtR)，内脏肥胖指数（VAI），脂质积累产物指数（LAP），和心脏代谢指数（CMI）与ISH。
这项横断面研究招募了106,248名接受常规健康筛查且舒张压不超过90mmHg的成年人。使用多元回归评估这些指标与ISH之间的关联。
传统肥胖指标（尤其是WHR和WHtR）的每个标准偏差（SD）增加的多变量校正比值比（OR）明显高于脂质相关肥胖指标的每个SD增加。此外,第三期ISH的多变量调整后OR(vs.1)传统肥胖指标也显著高于血脂相关指标。此外，传统肥胖指标在鉴别ISH方面的ROC曲线下面积高于脂质相关肥胖指标.
在中国成年人中，传统肥胖指标与ISH的相关性比与血脂相关的肥胖指标更强。
这项横断面研究招募了106,248名接受常规健康筛查且舒张压不超过90mmHg的成年人。使用多元回归评估这些指标与ISH之间的关联。
传统肥胖指标（尤其是WHR和WHtR）的每个标准偏差（SD）增加的多变量校正比值比（OR）明显高于脂质相关肥胖指标的每个SD增加。此外,第三期ISH的多变量调整后OR(vs.1)传统肥胖指标也显著高于血脂相关指标。此外，传统肥胖指标在鉴别ISH方面的ROC曲线下面积高于脂质相关肥胖指标.
在中国成年人中，传统肥胖指标与ISH的相关性比与血脂相关的肥胖指标更强。
