关键词: Head and neck pathology Immunohistochemistry Molecular genetics Sarcoma Soft tissue

Mesh : Head and Neck Neoplasms Humans Soft Tissue Neoplasms / pathology World Health Organization

来  源:   DOI:10.1007/s12105-022-01425-w

Abstract:
The fifth (5th) edition of the World Health Organization (WHO) Classification of Head and Neck Tumors introduces a new chapter dedicated to soft tissue neoplasms commonly affecting the head and neck. While the diversity, rarity, and wide anatomic range of soft tissue tumors precludes a discussion of all entities that may be found in the head and neck, the addition of this new chapter to the head and neck \"blue book\" aims to provide a more comprehensive and uniform reference text, including updated diagnostic criteria, of mesenchymal tumor types frequently (or exclusively) arising at head and neck sites. Since publication of the previous edition in 2017, there have been numerous advances in our understanding of the pathogenesis of many soft tissue tumors which have facilitated refinements in tumor classification, identification of novel entities, development of diagnostic markers, and improved prognostication. This review will provide a focused discussion of the soft tissue tumors included in the 5th edition WHO Head and Neck classification, with an emphasis on updates.
摘要:
世界卫生组织(WHO)头颈部肿瘤分类的第五版(第5版)介绍了专门针对通常影响头颈部的软组织肿瘤的新篇章。虽然多样性,稀有,和软组织肿瘤的广泛解剖范围排除了对可能在头颈部发现的所有实体的讨论,在头颈部“蓝皮书”中增加这一新章节,旨在提供更全面和统一的参考文本,包括更新的诊断标准,经常(或专门)出现在头颈部部位的间充质肿瘤类型。自2017年上一版出版以来,我们对许多软组织肿瘤的发病机理的理解取得了许多进展,这促进了肿瘤分类的改进。新实体的识别,诊断标记的发展,和改善预测。这篇综述将对第5版WHO头颈部分类中的软组织肿瘤进行重点讨论。强调更新。
公众号