Abstract：
Reporting of research for stroke-related visual impairment is inconsistent. The aim of this study was to define three core outcome sets (COS) and related core outcome measurements (COM) for central visual impairment, visual field loss and ocular motility disorders in stroke research.
The consensus process consisted of an online three-round Delphi survey followed by a consensus meeting of key stakeholders.
UK-wide survey.
Stakeholders included orthoptists, occupational therapists, ophthalmologists, stroke survivors and COS users such as researchers, journal editors and guideline developers.
For COS development, a list of potentially relevant visual outcomes was created after review of the literature and further grouped into outcome domains. For COM development, a list of potential instruments was created after review of the literature and quality appraised for reliability and validity.
COS-119 potential outcomes extracted from published literature. Similar assessment outcomes were grouped into 24 outcome domains. Delphi process included 123 participants in round 1, 65 round 2, 51 round 3. Twelve participants attended the consensus meeting with recommended outcome domains for central visual impairment (visual acuity, functional vision, quality of life), visual field loss (visual fields, functional vision, quality of life) and ocular motility disorders (eye alignment, eye movements, functional vision, quality of life). COM-52 test options extracted from the COS outcomes and grouped into 16 domains. Thirteen participants attended the COM consensus meeting. Recommended instruments for measurement of these outcomes include; Logarithm of the Minimal Angle of Resolution visual acuity, cover test, cardinal position eye movement assessments, peripheral visual field perimetry, Visual Function Questionnaire-25.
COS and COM are defined for vision research for stroke survivors. Their use has potential to reduce heterogeneity in routine clinical practice and improve standardisation and accuracy of vision assessment. Future research is required to evaluate the use of these COS and COM.
The consensus process consisted of an online three-round Delphi survey followed by a consensus meeting of key stakeholders.
UK-wide survey.
Stakeholders included orthoptists, occupational therapists, ophthalmologists, stroke survivors and COS users such as researchers, journal editors and guideline developers.
For COS development, a list of potentially relevant visual outcomes was created after review of the literature and further grouped into outcome domains. For COM development, a list of potential instruments was created after review of the literature and quality appraised for reliability and validity.
COS-119 potential outcomes extracted from published literature. Similar assessment outcomes were grouped into 24 outcome domains. Delphi process included 123 participants in round 1, 65 round 2, 51 round 3. Twelve participants attended the consensus meeting with recommended outcome domains for central visual impairment (visual acuity, functional vision, quality of life), visual field loss (visual fields, functional vision, quality of life) and ocular motility disorders (eye alignment, eye movements, functional vision, quality of life). COM-52 test options extracted from the COS outcomes and grouped into 16 domains. Thirteen participants attended the COM consensus meeting. Recommended instruments for measurement of these outcomes include; Logarithm of the Minimal Angle of Resolution visual acuity, cover test, cardinal position eye movement assessments, peripheral visual field perimetry, Visual Function Questionnaire-25.
COS and COM are defined for vision research for stroke survivors. Their use has potential to reduce heterogeneity in routine clinical practice and improve standardisation and accuracy of vision assessment. Future research is required to evaluate the use of these COS and COM.
摘要：
卒中相关视力损害的研究报告不一致。这项研究的目的是定义三个核心结果集（COS）和相关的核心结果测量（COM）中心视力障碍，脑卒中视野丧失和眼运动障碍的研究。
共识过程包括在线三轮Delphi调查，然后是关键利益相关者的共识会议。
英国范围的调查。
利益相关者包括骨科医师，职业治疗师,眼科医生,中风幸存者和COS使用者，如研究人员，期刊编辑和指南开发人员。
对于COS开发，在回顾文献后,我们创建了潜在相关的视觉结局列表,并将其进一步分组为结局领域.对于COM开发，在回顾文献和质量评估的信度和效度后,我们创建了一份潜在工具清单.
从已发表的文献中提取的COS-119潜在结果。相似的评估结果分为24个结果域。德尔菲进程包括第1轮、第2轮、第51轮第3轮的123名参与者。12名参与者参加了共识会议，推荐了中央视力障碍的结果域（视敏度，功能视觉，生活质量)，视野损失(视野，功能视觉，生活质量)和眼运动障碍(眼睛排列，眼球运动,功能视觉，生活质量)。从COS结果中提取的COM-52测试选项，分为16个领域。13名与会者出席了COM共识会议。用于测量这些结果的推荐仪器包括；最小分辨率视敏度角度的对数，覆盖试验,基本位置眼动评估，周边视野，视觉功能问卷-25.
COS和COM被定义为中风幸存者的视力研究。它们的使用有可能减少常规临床实践中的异质性，并提高视力评估的标准化和准确性。需要进一步的研究来评估这些COS和COM的使用。
共识过程包括在线三轮Delphi调查，然后是关键利益相关者的共识会议。
英国范围的调查。
利益相关者包括骨科医师，职业治疗师,眼科医生,中风幸存者和COS使用者，如研究人员，期刊编辑和指南开发人员。
对于COS开发，在回顾文献后,我们创建了潜在相关的视觉结局列表,并将其进一步分组为结局领域.对于COM开发，在回顾文献和质量评估的信度和效度后,我们创建了一份潜在工具清单.
从已发表的文献中提取的COS-119潜在结果。相似的评估结果分为24个结果域。德尔菲进程包括第1轮、第2轮、第51轮第3轮的123名参与者。12名参与者参加了共识会议，推荐了中央视力障碍的结果域（视敏度，功能视觉，生活质量)，视野损失(视野，功能视觉，生活质量)和眼运动障碍(眼睛排列，眼球运动,功能视觉，生活质量)。从COS结果中提取的COM-52测试选项，分为16个领域。13名与会者出席了COM共识会议。用于测量这些结果的推荐仪器包括；最小分辨率视敏度角度的对数，覆盖试验,基本位置眼动评估，周边视野，视觉功能问卷-25.
COS和COM被定义为中风幸存者的视力研究。它们的使用有可能减少常规临床实践中的异质性，并提高视力评估的标准化和准确性。需要进一步的研究来评估这些COS和COM的使用。
