Abstract：
The aim of this study was evaluate to seroprevalence of Toxoplasma gondii in goats worldwide and the main risk factors associated from 2000 to 2020, through meta-analysis with 55,317 goats from 75 reports published in seven electronic databases of major global importance. A global seroprevalence detected was 27.49% (95% CI 24.15-30.95; I2 = 99%), with the lowest percentage in Asia (20.74%; 95% CI 16.45-25.39) and highest in Central America (62.15%; 95% CI 57.28-66.90) and Europe (31.53%; 95% CI 21.71-42.26). The seropositivity in Africa and South America were (29.41%; 95% CI 19.11-40.89) and (29.76%; 95% CI 25.84-33.83), respectively. The seroprevalence was associated with presence of cats (OR 2.22; 95% CI 1.30-3.82), goats older than one year (OR 1.77; 95% CI 1, 37-2.29), females (OR 1.43; 95% CI 1.23-1.65), rearing system (extensive vs. intensive) (OR 4.82; 95% CI 1.96-11, 84) and rearing system (semi-intensive vs. intensive) (OR 1.48; 95% CI 1.48-6.13). The heterogeneity was evidenced in most world regions and the risk factors may play roles in varying the seroprevalence.
摘要：
这项研究的目的是通过对发表在七个具有全球重要性的电子数据库中的75份报告中的55,317只山羊进行荟萃分析，评估全球山羊弓形虫的血清阳性率以及2000年至2020年的主要危险因素。检测到的总体血清阳性率为27.49％（95％CI24.15-30.95；I2=99％），亚洲比例最低（20.74%；95%CI16.45-25.39），中美洲最高（62.15%；95%CI57.28-66.90）和欧洲最高（31.53%；95%CI21.71-42.26）。非洲和南美的血清阳性分别为（29.41％;95％CI19.11-40.89）和（29.76％;95％CI25.84-33.83），分别。血清阳性率与猫的存在相关（OR2.22;95％CI1.30-3.82），一岁以上的山羊（OR1.77；95%CI1，37-2.29），女性（OR1.43；95%CI1.23-1.65），饲养系统(广泛与密集）（OR4.82；95%CI1.96-11，84）和饲养系统（半密集与密集）（OR1.48；95%CI1.48-6.13）。异质性在世界大多数地区得到证实，危险因素可能在血清阳性率的变化中起作用。
