PDF(Pubmed)
Abstract：
With the development of three-dimensional (3D) printed technology, 3D printed alloy implants, especially titanium alloy, play a critical role in biomedical fields such as orthopedics and dentistry. However, untreated titanium alloy implants always possess a bioinert surface that prevents the interface osseointegration, which is necessary to perform surface modification to enhance its biological functions. In this article, we discuss the principles and processes of chemical, physical, and biological surface modification technologies on 3D printed titanium alloy implants in detail. Furthermore, the challenges on antibacterial, osteogenesis, and mechanical properties of 3D-printed titanium alloy implants by surface modification are summarized. Future research studies, including the combination of multiple modification technologies or the coordination of the structure and composition of the composite coating are also present. This review provides leading-edge functionalization strategies of the 3D printed titanium alloy implants.
摘要：
随着3D打印技术的发展,3D打印合金植入物，特别是钛合金，在生物医学领域，如骨科和牙科发挥关键作用。然而,未经处理的钛合金植入物总是具有生物惰性表面，防止界面骨整合，这是进行表面改性以增强其生物学功能所必需的。在这篇文章中,我们讨论化学的原理和过程，物理，和生物表面改性技术在3D打印钛合金植入物上的应用。此外，抗菌方面的挑战，成骨,总结了3D打印钛合金植入物表面改性的力学性能。未来的研究，包括多种改性技术的组合或复合涂层的结构和组成的协调也是存在的。这篇综述提供了3D打印钛合金植入物的前沿功能化策略。
