PDF(Pubmed)
Abstract：
A growing evidence base has implicated immune dysfunction in the etiology of some cases of autism spectrum disorder. The precise relationship between immune disorders and autism spectrum disorder remains unclear. Herein we report a 14-year-old-male with agammaglobulinemia, who was diagnosed with autism spectrum disorder, and who has received exogenous immunoglobulins regularly for most of his life. This case study supports current theories implicating antibody deficiencies in some individuals with an autism spectrum disorder. Our case will add to the growing literature of understanding the connection between immune deficiencies in the pathogenesis of autism.
摘要：
越来越多的证据表明，某些自闭症谱系障碍的病因涉及免疫功能障碍。免疫疾病与自闭症谱系障碍之间的确切关系尚不清楚。在这里，我们报告了一名14岁的男性患有无丙种球蛋白血症，他被诊断出患有自闭症谱系障碍，他一生中经常接受外源性免疫球蛋白。该案例研究支持当前的理论，这些理论涉及某些自闭症谱系障碍患者的抗体缺乏。我们的案例将增加越来越多的文献，以了解自闭症发病机制中免疫缺陷之间的联系。
