Abstract：
Laparoscopic sleeve gastrectomy (SG) is a common and effective bariatric surgery, with low postoperative complication rates. It is important to define modifiable risk factors for complications. The possible association of Helicobacter pylori (HP) on SG outcomes is still being investigated. We aimed to examine HP prevalence in SG specimens, the association to early (30-day) complications, and impact of preoperative HP eradication on outcomes.
This is a retrospective analysis of all consecutive patients who underwent SG between January 2012 and December 2020 in a single bariatric center. Data were retrieved from our prospectively maintained patient registry database. The 30-day outcomes were compared according to the HP status of the resected specimen: positive and negative, with or without preoperative HP eradication therapy.
There were 1985 patients; of them, 179 patients were HP positive and 1806 were HP negative in resected specimens. The overall early complication and major (Clavien-Dindo ≥ 3) complication rates were 8.6% and 3.2% (p = 0.48 and p = 0.21), respectively. A total of 111 patients were HP positive on preoperative endoscopic biopsy and received eradication therapy. All were HP negative on preoperative urea breath test, and 65.45% had HP negative resected specimens. HP eradication did not affect overall and major complications (p = 0.68 and p = 0.48, respectively).
The presence of HP does not seem to affect the early outcomes of SG. HP eradication does not change the early postoperative course either. Therefore, the role of routine preoperative HP screening may be limited, and eradication can be completed following SG.
This is a retrospective analysis of all consecutive patients who underwent SG between January 2012 and December 2020 in a single bariatric center. Data were retrieved from our prospectively maintained patient registry database. The 30-day outcomes were compared according to the HP status of the resected specimen: positive and negative, with or without preoperative HP eradication therapy.
There were 1985 patients; of them, 179 patients were HP positive and 1806 were HP negative in resected specimens. The overall early complication and major (Clavien-Dindo ≥ 3) complication rates were 8.6% and 3.2% (p = 0.48 and p = 0.21), respectively. A total of 111 patients were HP positive on preoperative endoscopic biopsy and received eradication therapy. All were HP negative on preoperative urea breath test, and 65.45% had HP negative resected specimens. HP eradication did not affect overall and major complications (p = 0.68 and p = 0.48, respectively).
The presence of HP does not seem to affect the early outcomes of SG. HP eradication does not change the early postoperative course either. Therefore, the role of routine preoperative HP screening may be limited, and eradication can be completed following SG.
摘要：
腹腔镜袖状胃切除术（SG）是一种常见而有效的减肥手术，术后并发症发生率低。定义可改变的并发症危险因素很重要。幽门螺杆菌（HP）与SG结局的可能关联仍在研究中。我们的目的是检查SG标本中的HP患病率，早期（30天）并发症的关联，以及术前HP根除对结局的影响。
这是对2012年1月至2020年12月在单一减肥中心接受SG的所有连续患者的回顾性分析。从我们前瞻性维护的患者注册数据库中检索数据。根据切除标本的HP状态比较30天结果：阳性和阴性，术前有或没有HP根除治疗。
有1985个病人，其中，切除标本中HP阳性179例，HP阴性1806例。总体早期并发症和主要(Clavien-Dindo≥3)并发症发生率分别为8.6%和3.2%(p=0.48和p=0.21)。分别。共有111例患者在术前内镜活检中HP阳性，并接受了根除治疗。术前尿素呼气试验HP阴性，HP阴性切除标本占65.45%。HP根除不影响总体和主要并发症（分别为p=0.68和p=0.48）。
HP的存在似乎并不影响SG的早期结果。HP根除也不会改变术后早期的病程。因此,常规术前HP筛查的作用可能有限，根除可以在SG之后完成。
这是对2012年1月至2020年12月在单一减肥中心接受SG的所有连续患者的回顾性分析。从我们前瞻性维护的患者注册数据库中检索数据。根据切除标本的HP状态比较30天结果：阳性和阴性，术前有或没有HP根除治疗。
有1985个病人，其中，切除标本中HP阳性179例，HP阴性1806例。总体早期并发症和主要(Clavien-Dindo≥3)并发症发生率分别为8.6%和3.2%(p=0.48和p=0.21)。分别。共有111例患者在术前内镜活检中HP阳性，并接受了根除治疗。术前尿素呼气试验HP阴性，HP阴性切除标本占65.45%。HP根除不影响总体和主要并发症（分别为p=0.68和p=0.48）。
HP的存在似乎并不影响SG的早期结果。HP根除也不会改变术后早期的病程。因此,常规术前HP筛查的作用可能有限，根除可以在SG之后完成。
