关键词: IVF IVF outcome Long GnRH agonist protocol Oocyte retrieval rhCG IVF IVF outcome Long GnRH agonist protocol Oocyte retrieval rhCG

Mesh : Adult Analysis of Variance Chorionic Gonadotropin / administration & dosage Cohort Studies Female Fertilization in Vitro / methods Humans Middle East Oocyte Retrieval Ovulation Induction / methods Pregnancy Pregnancy Rate Recombinant Proteins / administration & dosage Reproductive Control Agents / administration & dosage Time Factors Adult Analysis of Variance Chorionic Gonadotropin / administration & dosage Cohort Studies Female Fertilization in Vitro / methods Humans Middle East Oocyte Retrieval Ovulation Induction / methods Pregnancy Pregnancy Rate Recombinant Proteins / administration & dosage Reproductive Control Agents / administration & dosage Time Factors

来  源:   DOI:10.1186/s12884-022-04412-9

Abstract:
BACKGROUND: Our objective was to investigate the existence of an optimal period for oocyte retrieval in regards to the clinical pregnancy occurrence after the administration of recombinant human chorionic gonadotropin (rhCG) (Ovitrelle®).
METHODS: We studied the digital records of 3362 middle eastern couples who underwent in vitro fertilization (IVF) treatment between 2019 and 2021.
RESULTS: Through statistical testing, we found that there is a significant positive correlation between the oocyte retrieval period and the clinical pregnancy occurrence up to the 37th hour, where retrieval at the 37th hour was found to provide the most optimal outcome, especially in the case of gonadotropin-releasing hormone agonist (GnRHa) long protocol.
CONCLUSIONS: This cohort study recommends retrieval at hour 37 after ovulation triggering under the described conditions.
摘要:
背景:我们的目的是研究在施用重组人绒毛膜促性腺激素(rhCG)(Ovitrelle®)后,在临床妊娠发生方面是否存在取卵期。
方法:我们研究了在2019年至2021年间接受体外受精(IVF)治疗的3362对中东夫妇的数字记录。
结果:通过统计检验,我们发现,直到第37小时,取卵期与临床妊娠发生之间存在显着正相关,在第37小时的检索被发现提供了最佳的结果,特别是在促性腺激素释放激素激动剂(GnRHa)长方案的情况下。
结论:本队列研究建议在上述条件下,在排卵触发后第37小时进行检索。
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