METHODS: An 82-year-old man was referred to our hospital for investigation of gross hematuria. Magnetic resonance imaging revealed nodules measuring 1-2 mm in diameter in the left upper ureter with slight reduction in signal intensity on diffusion-weighted imaging. Ureteroscopy showed a pedunculated smooth tumor that had the appearance of an inverted papilloma rather than the papillary shape typical of urothelial carcinoma. The tumor was biopsied and histopathological examination revealed a noninvasive, low-grade urothelial carcinoma with inverted multiple layers. Laparoscopic radical nephroureterectomy was subsequently performed, and a pedunculated tumor measuring 20 mm in diameter was found in the left upper ureter. The histopathological diagnosis was inverted papillary urothelial carcinoma, low-grade, pTa, pN0.
CONCLUSIONS: This report provides the first clinical description of inverted papillary urothelial carcinoma of the ureter.
方法:将一名82岁的男子转诊到我院进行肉眼血尿调查。磁共振成像显示,左上输尿管直径为1-2mm的结节,扩散加权成像的信号强度略有降低。输尿管镜检查显示有蒂的平滑肿瘤,具有倒置的乳头状瘤的外观,而不是尿路上皮癌典型的乳头状形状。对肿瘤进行活检,组织病理学检查显示非侵入性,低级别尿路上皮癌伴多层倒置。随后进行了腹腔镜根治性肾输尿管切除术,在左上输尿管发现了一个直径20毫米的带蒂肿瘤。组织病理学诊断为倒置型乳头状尿路上皮癌,低档,pTa,pN0。
结论:本报告首次提供输尿管内翻性乳头状尿路上皮癌的临床描述。