{Reference Type}: Case Reports {Title}: Case of inverted papillary urothelial carcinoma in the ureter. {Author}: Nirei T;Nakaigawa N;Matsumura M;Kataoka T;Nagasaka T;Aomori K;Ito Y;Muraoka K;Yao M; {Journal}: IJU Case Rep {Volume}: 5 {Issue}: 2 {Year}: Mar 2022 暂无{DOI}: 10.1002/iju5.12403 {Abstract}: BACKGROUND: Urothelial neoplasms with a varus growth pattern are rare, and few urologists have encountered inverted urothelial carcinoma of the ureter.
METHODS: An 82-year-old man was referred to our hospital for investigation of gross hematuria. Magnetic resonance imaging revealed nodules measuring 1-2 mm in diameter in the left upper ureter with slight reduction in signal intensity on diffusion-weighted imaging. Ureteroscopy showed a pedunculated smooth tumor that had the appearance of an inverted papilloma rather than the papillary shape typical of urothelial carcinoma. The tumor was biopsied and histopathological examination revealed a noninvasive, low-grade urothelial carcinoma with inverted multiple layers. Laparoscopic radical nephroureterectomy was subsequently performed, and a pedunculated tumor measuring 20 mm in diameter was found in the left upper ureter. The histopathological diagnosis was inverted papillary urothelial carcinoma, low-grade, pTa, pN0.
CONCLUSIONS: This report provides the first clinical description of inverted papillary urothelial carcinoma of the ureter.