Abstract：
BACKGROUND: The goal of this study was to determine how to translate visual analogue scale (VAS) symptom scores to the binary, descriptive symptom scales used in the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) criteria for chronic rhinosinusitis (CRS) disease control.
METHODS: 309 CRS patients were recruited. All patients rated their burden of 5 symptoms (nasal blockage, rhinorrhea/postnasal drip, facial pain/pressure, smell loss, sleep disturbance or fatigue) using the binary EPOS descriptive symptom scales and a VAS (on a scale of 0 to 10). In addition, participants completed a 22-item Sinonasal Outcome Test (SNOT-22) and rated their overall CRS disease control as \"controlled\", \"partly controlled\" or \"uncontrolled\" Results: Symptom burdens measured by VAS, binary descriptive EPOS scale and SNOT-22 were associated with worsening CRS disease control reported by participants. Each symptom had a distinct VAS score cut-off that strongly predicted the uncontrolled option on the corresponding binary descriptive EPOS symptom scale. However, the predictive ability of VAS for rhinorrhea/ postnasal drip was disparately worse than the other 4 symptoms. When considering all symptom data simultaneously, a VAS score higher than 3.5 strongly predicted the uncontrolled option on the corresponding binary descriptive EPOS symptom scale for all 5 symptoms.
CONCLUSIONS: A VAS symptom score of higher than 3.5 translates to the uncontrolled option in the binary, descriptive symptom scale of the EPOS control criteria. The rhinorrhea/postnasal drip descriptive symptom scale translates disparately worse to VAS scores and may be considered for revision in future criteria.
METHODS: 309 CRS patients were recruited. All patients rated their burden of 5 symptoms (nasal blockage, rhinorrhea/postnasal drip, facial pain/pressure, smell loss, sleep disturbance or fatigue) using the binary EPOS descriptive symptom scales and a VAS (on a scale of 0 to 10). In addition, participants completed a 22-item Sinonasal Outcome Test (SNOT-22) and rated their overall CRS disease control as \"controlled\", \"partly controlled\" or \"uncontrolled\" Results: Symptom burdens measured by VAS, binary descriptive EPOS scale and SNOT-22 were associated with worsening CRS disease control reported by participants. Each symptom had a distinct VAS score cut-off that strongly predicted the uncontrolled option on the corresponding binary descriptive EPOS symptom scale. However, the predictive ability of VAS for rhinorrhea/ postnasal drip was disparately worse than the other 4 symptoms. When considering all symptom data simultaneously, a VAS score higher than 3.5 strongly predicted the uncontrolled option on the corresponding binary descriptive EPOS symptom scale for all 5 symptoms.
CONCLUSIONS: A VAS symptom score of higher than 3.5 translates to the uncontrolled option in the binary, descriptive symptom scale of the EPOS control criteria. The rhinorrhea/postnasal drip descriptive symptom scale translates disparately worse to VAS scores and may be considered for revision in future criteria.
摘要：
背景：这项研究的目的是确定如何将视觉模拟量表（VAS）症状评分转化为二进制，用于慢性鼻-鼻窦炎(CRS)疾病控制的鼻-鼻窦炎和鼻息肉(EPOS)标准的欧洲立场文件中的描述性症状量表。
方法：招募了309名CRS患者。所有患者都评估了他们的5种症状负担（鼻塞，鼻漏/鼻后滴漏，面部疼痛/压力，气味损失,睡眠障碍或疲劳）使用二元EPOS描述性症状量表和VAS（0至10的量表）。此外,参与者完成了22项鼻窦结果测试（SNOT-22），并将他们的CRS疾病总体控制评分为“控制”，\"部分受控\"或\"不受控\"。
结果：通过VAS测量的症状负担，二元描述性EPOS量表和SNOT-22与参与者报告的CRS疾病控制恶化相关.每种症状都有不同的VAS评分截止值，可以在相应的二元描述性EPOS症状量表上强烈预测不受控制的选择。然而,VAS对鼻漏/鼻后滴漏的预测能力远不如其他4种症状。当同时考虑所有症状数据时，VAS评分>3.5在所有5种症状的相应二元描述性EPOS症状量表上强烈预测了不受控制的选择。
结论：>3.5的VAS症状评分转化为二元模型中的不受控制选项，EPOS控制标准的描述性症状量表。鼻漏/鼻后滴注描述性症状量表对VAS评分的翻译程度不同，可能会考虑在将来的标准中进行修订。
方法：招募了309名CRS患者。所有患者都评估了他们的5种症状负担（鼻塞，鼻漏/鼻后滴漏，面部疼痛/压力，气味损失,睡眠障碍或疲劳）使用二元EPOS描述性症状量表和VAS（0至10的量表）。此外,参与者完成了22项鼻窦结果测试（SNOT-22），并将他们的CRS疾病总体控制评分为“控制”，\"部分受控\"或\"不受控\"。
结果：通过VAS测量的症状负担，二元描述性EPOS量表和SNOT-22与参与者报告的CRS疾病控制恶化相关.每种症状都有不同的VAS评分截止值，可以在相应的二元描述性EPOS症状量表上强烈预测不受控制的选择。然而,VAS对鼻漏/鼻后滴漏的预测能力远不如其他4种症状。当同时考虑所有症状数据时，VAS评分>3.5在所有5种症状的相应二元描述性EPOS症状量表上强烈预测了不受控制的选择。
结论：>3.5的VAS症状评分转化为二元模型中的不受控制选项，EPOS控制标准的描述性症状量表。鼻漏/鼻后滴注描述性症状量表对VAS评分的翻译程度不同，可能会考虑在将来的标准中进行修订。
