PDF(Pubmed)
Abstract：
Chronic portal vein thrombosis (PVT) is a major vascular complication of liver cirrhosis. Patients may be asymptomatic and chronic PVT might be detected incidentally on imaging. PVT is associated with worsening liver disease, poorer clinical outcomes, and might proceed to life-threatening intestinal ischemia. Management of chronic PVT with anticoagulation has been shown to be successful in promoting recanalization and reducing thrombus extension in patients with cirrhosis. However, optimal anticoagulation for PVT in cirrhosis has not yet been addressed in any large-scale trial, and the decision to anti-coagulate varies on a case by case presentation. We report the case of a 62-year-old male patient with a history of liver cirrhosis, pancytopenia, and grade II esophageal varices presenting with abdominal pain who was incidentally found to have chronic thrombosis of the portal vein on imaging and was managed appropriately with a good outcome.
摘要：
慢性门静脉血栓形成（PVT）是肝硬化的主要血管并发症。患者可能无症状，并且在影像学检查中可能偶然发现慢性PVT。PVT与肝脏疾病恶化有关，较差的临床结果，可能会导致危及生命的肠缺血.抗凝治疗慢性PVT已被证明可以成功促进肝硬化患者的再通和减少血栓延伸。然而,肝硬化PVT的最佳抗凝治疗尚未在任何大规模试验中得到解决，抗凝的决定因病例而异。我们报道一例62岁男性患者，有肝硬化病史，全血细胞减少症,和表现为腹痛的II级食管静脉曲张，在影像学上偶然发现门静脉慢性血栓形成，并得到适当的治疗，结果良好。
