Abstract：
OBJECTIVE: To compare the progression of posterior vitreous detachment (PVD) after cataract surgery in eyes with high myopia with that in eyes without high myopia.
METHODS: Prospective observational study.
METHODS: Eighty eyes of 80 patients with high myopia and 160 eyes of 160 patients without high myopia scheduled for phacoemulsification were recruited. PVD status was examined using swept-source optical coherence tomography at 2 days postoperatively (baseline) and at 3, 6, and 12 months postbaseline and classified into 5 stages: 0 (no PVD), 1 (paramacular PVD), 2 (perifoveal PVD), 3 (peripapillary PVD), and 4 (complete PVD). The PVD stage and incidence of progression to complete PVD of the 2 groups were compared.
RESULTS: The mean PVD stage did not differ significantly between the groups at baseline or at 3 months postbaseline but was significantly more progressed in the high myopia group than in the nonhigh myopia group at 6 months and 12 months postbaseline (P ≤ 0.0201). The Kaplan-Meier survival rate for complete PVD was significantly lower in the high myopia group (P = 0.0129). After adjusting for age, sex, and baseline PVD stage, the hazard ratio for complete PVD was 1.68-fold higher in the high myopia group than in the nonhigh myopia group (P = 0.0326, 95% CI 1.04-2.70).
CONCLUSIONS: After cataract surgery, PVD progressed significantly faster in eyes with high myopia than in eyes without high myopia, and the relative risk for complete PVD was 1.68-fold higher in eyes with high myopia, suggesting that highly myopic eyes are at considerably high risk for retinal disease postoperatively.
METHODS: Prospective observational study.
METHODS: Eighty eyes of 80 patients with high myopia and 160 eyes of 160 patients without high myopia scheduled for phacoemulsification were recruited. PVD status was examined using swept-source optical coherence tomography at 2 days postoperatively (baseline) and at 3, 6, and 12 months postbaseline and classified into 5 stages: 0 (no PVD), 1 (paramacular PVD), 2 (perifoveal PVD), 3 (peripapillary PVD), and 4 (complete PVD). The PVD stage and incidence of progression to complete PVD of the 2 groups were compared.
RESULTS: The mean PVD stage did not differ significantly between the groups at baseline or at 3 months postbaseline but was significantly more progressed in the high myopia group than in the nonhigh myopia group at 6 months and 12 months postbaseline (P ≤ 0.0201). The Kaplan-Meier survival rate for complete PVD was significantly lower in the high myopia group (P = 0.0129). After adjusting for age, sex, and baseline PVD stage, the hazard ratio for complete PVD was 1.68-fold higher in the high myopia group than in the nonhigh myopia group (P = 0.0326, 95% CI 1.04-2.70).
CONCLUSIONS: After cataract surgery, PVD progressed significantly faster in eyes with high myopia than in eyes without high myopia, and the relative risk for complete PVD was 1.68-fold higher in eyes with high myopia, suggesting that highly myopic eyes are at considerably high risk for retinal disease postoperatively.
摘要：
目的：比较高度近视眼与非高度近视眼白内障术后玻璃体后脱离(PVD)的进展。
方法：前瞻性观察性研究。
方法：收集80例高度近视患者80只眼和160例非高度近视患者160只眼进行超声乳化手术。在术后2天（基线）和基线后3、6和12个月使用扫频光源光学相干断层扫描检查PVD状态，并分为5个阶段：0（无PVD），1（顺行PVD），2（中央凹PVD），3（乳头周围PVD），和4（完全PVD）。比较2组的PVD分期和进展至完全PVD的发生率。
结果：两组在基线时或基线后3个月时的平均PVD分期没有显著差异，但在基线后6个月和12个月时，高度近视组比非高度近视组的进展显著(P≤0.0201)。高度近视组完全PVD的Kaplan-Meier生存率明显降低(P=0.0129)。在调整了年龄之后,性别,和基线PVD阶段，高度近视组完全PVD的风险比为非高度近视组的1.68倍(P=0.0326,95%CI1.04~2.70).
结论：白内障手术后，高度近视眼的PVD进展明显快于非高度近视眼，高度近视眼完全PVD的相对风险高1.68倍，表明高度近视的眼睛在术后发生视网膜疾病的风险相当高。
方法：前瞻性观察性研究。
方法：收集80例高度近视患者80只眼和160例非高度近视患者160只眼进行超声乳化手术。在术后2天（基线）和基线后3、6和12个月使用扫频光源光学相干断层扫描检查PVD状态，并分为5个阶段：0（无PVD），1（顺行PVD），2（中央凹PVD），3（乳头周围PVD），和4（完全PVD）。比较2组的PVD分期和进展至完全PVD的发生率。
结果：两组在基线时或基线后3个月时的平均PVD分期没有显著差异，但在基线后6个月和12个月时，高度近视组比非高度近视组的进展显著(P≤0.0201)。高度近视组完全PVD的Kaplan-Meier生存率明显降低(P=0.0129)。在调整了年龄之后,性别,和基线PVD阶段，高度近视组完全PVD的风险比为非高度近视组的1.68倍(P=0.0326,95%CI1.04~2.70).
结论：白内障手术后，高度近视眼的PVD进展明显快于非高度近视眼，高度近视眼完全PVD的相对风险高1.68倍，表明高度近视的眼睛在术后发生视网膜疾病的风险相当高。
