Abstract：
Wilms tumor is the most common primary renal malignancy in pediatric age group, however, is rare in adults accounting for 0.5% of all adult renal malignancies. The histopathology is similar in both age groups, however the prognosis in adults is poor with tumor being at advanced stage at presentation with increased incidence of metastasis. Due to rare occurrence in adults and lack of differentiating clinical and imaging features its diagnosis is delayed or often misdiagnosed as adult renal cell cancer. Pre surgical or early post-surgical chemotherapy has shown significantly better surgical outcome and survival rate, however, delayed or misdiagnosis precludes or delays the chemotherapy. Lack of standardized treatment guidelines for adults also adds to the poor prognosis. Presurgical biopsy of renal masses in young adults can be suggested for early diagnosis as well as inclusion of presurgical chemotherapy for overall better outcome.
摘要：
肾母细胞瘤是儿童年龄组中最常见的原发性肾脏恶性肿瘤，然而,在成人中很少见，占所有成人肾脏恶性肿瘤的0.5％。两个年龄组的组织病理学相似，然而，成人的预后较差，肿瘤在转移发生率增加的情况下处于晚期。由于成人罕见且缺乏鉴别临床和影像学特征，其诊断被延迟或经常误诊为成人肾细胞癌。术前或术后早期化疗显示出明显更好的手术效果和生存率，然而,延迟或误诊排除或延迟化疗。缺乏成人的标准化治疗指南也增加了不良预后。可以建议对年轻人的肾脏肿块进行术前活检以进行早期诊断，并包括术前化疗以获得更好的总体结果。
