Abstract：
Wernicke-Korsakoff syndrome is the best known consequence of thiamine deficiency, frequently associated with patients with chronic and excessive alcohol consumption, but it can be produced by any cause that produces thiamine deficiency. The disease is underdiagnosed so it is essential to have a high clinical suspicion, mainly in patients who do not have alcohol consumption as a risk factor. For this, the diagnosis continues to be eminently clinical, with the difficulty of high clinical variability. Complementary tests are used to support the diagnosis and rule out other causes that can produce similar symptoms, with magnetic resonance imaging being the most cost-effective imaging test. Treatment is based on the administration of thiamine, which should be started early, and parenterally at the appropriate doses, in all patients with compatible symptoms, without waiting to confirm the diagnosis.
摘要：
Wernicke-Korsakoff综合征是众所周知的硫胺素缺乏的后果，经常与慢性和过度饮酒的患者有关，但它可以由任何导致硫胺素缺乏的原因产生。该疾病未被诊断，因此必须具有高度的临床怀疑，主要是在没有饮酒作为危险因素的患者中。为此，诊断仍然非常临床，具有高临床变异性的困难。补充测试用于支持诊断并排除可能产生类似症状的其他原因，磁共振成像是最具成本效益的成像测试。治疗是基于硫胺素的给药，应该早点开始，以适当的剂量肠胃外，在所有有相容症状的患者中，而不等待确认诊断。
