关键词: antibacterial cytidine self-healing silver acetate stimuli responsive thixotropic

来  源:   DOI:10.1021/acsabm.9b00438   PDF(Sci-hub)

Abstract:
We herein report the preparation of hydrogels by the Ag+ ion induced assembly of cytidine and boronic acids. These hydrogels, presumably formed by an i-motif like arrangement of cytidine and its boronate ester analogues, possess excellent thixotropic and self-healing properties. The hydrogels exhibit potent antimicrobial activity that can be tuned by varying the functional groups in their boronic acid component. These hydrogels could find potential use as antimicrobial agents and stimuli-responsive drug delivery systems.
摘要:
我们在此报道了通过Ag离子诱导的胞苷和硼酸组装制备水凝胶。这些水凝胶,推测由胞苷及其硼酸酯类似物的i-基序状排列形成,具有优良的触变性和自愈性能。水凝胶表现出有效的抗微生物活性,其可以通过改变其硼酸组分中的官能团来调节。这些水凝胶可以找到作为抗微生物剂和刺激响应性药物递送系统的潜在用途。
公众号