PDF(Sci-hub)
Abstract：
Nanomaterials used as novel antimicrobial agents are developed to combat wide-spectrum bacteria as well as alleviate the problem of bacterial resistance to traditional antibiotics. Two-dimensional (2D) nanomaterials are regarded as promising and widely applicable wide-spectrum antibacterial nanoagents due to their outstanding characteristics, including large surface area, stable structure, good biocompatibility, and cheap raw materials, especially excellent photocatalytic or photothermal properties. The advantages of less resistance, rapid sterilization, local action mode, and non-invasive make 2D nanomaterials with photoinduced property stand out in novel sterilization agents. Here, we systematically summarize various kinds of 2D nanomaterials that were used in photoinduced antibacterial field and introduce the synthesis methods and physicochemical properties related to antibacterial capability. Besides, the sterilization mechanisms of different 2D nanomaterials are also introduced in detail including a direct temperature generation, ROS production or ROS-independent oxidative stress, or various synergistic antibacterial modes. Lastly, we have also discussed the current problems of 2D nanomaterials as light-inducing antibacterial agents and their future application prospects in the fields of biomedicine, sewage treatment, food, and other application scenarios. We envision that this review will assist investigators with quick and in-depth understanding of the latest progress in 2D nanomaterials for photoinduced sterilization, inspiring the development of multiply strategies to design and synthesize novel 2D materials with strong bactericidal capability and high biological safety, and expand 2D materials with photoinduced sterilization to more application scenarios.
摘要：
纳米材料用作新型抗微生物剂被开发用于对抗广谱细菌以及缓解细菌对传统抗生素的耐药性问题。二维(2D)纳米材料因其优异的特性被认为是有前途和广泛适用的广谱抗菌纳米剂,包括大表面积，结构稳定,良好的生物相容性,和廉价的原材料，特别是优异的光催化或光热性能。阻力小的优点，快速灭菌,局部动作模式,非侵入性使具有光诱导特性的二维纳米材料在新型灭菌剂中脱颖而出。这里,系统总结了光诱导抗菌领域的各种二维纳米材料，介绍了与抗菌性能相关的合成方法和理化性质。此外,还详细介绍了不同二维纳米材料的灭菌机理，包括直接温度产生，ROS产生或ROS非依赖性氧化应激，或各种协同抗菌模式。最后,我们还讨论了二维纳米材料作为光诱导抗菌剂目前存在的问题及其在生物医学领域的未来应用前景，污水处理,食物,等应用场景。我们预计，这篇综述将有助于研究者快速深入地了解二维纳米材料在光致灭菌方面的最新进展，激发了多种策略的发展，以设计和合成具有强大杀菌能力和高生物安全性的新型2D材料，并将具有光诱导灭菌功能的2D材料扩展到更多的应用场景。
