Abstract：
The Global Program to Eliminate Lymphatic Filariasis (GPELF) is a program that aims to eliminate lymphatic filariasis by 2030. The GPELF strategy is based on interrupting transmission using mass drug administration (MDA) and, in parallel, managing morbidity cases. However, it has been seen that there is a shortage of research in the literature and public policies regarding this last pillar. In this study, we reviewed the literature and available information regarding the burden of filarial morbidity. In addition, we identified that in the Americas, the implementation of structured services with regard to morbidity assistance in the Americas was scarce. We formed a review that aimed to assess the pathogenesis, epidemiology, repercussions, and treatment of filarial morbidity in countries in the Americas where lymphatic filariasis is endemic. Structured searches were carried out on PubMed, LILACS, Scopus, and Web of Science databases without time and language restrictions. Three reviewers evaluated the 2150 studies and performed data extraction, and quality assessment by assigning scores to the studies found. The current literature and available information on the burden of filarial morbidity, as well as the implementation of structured services with regard to morbidity assistance in the Americas, were all found to be scarce. Now that this knowledge gap has been identified, both health services and researchers need to seek the implementation and enhancement of the maintenance of GPELF strategies that relate to the morbidity pillar.
摘要：
全球消除淋巴丝虫病计划（GPELF）是一个旨在到2030年消除淋巴丝虫病的计划。GPELF策略基于使用大规模药物管理(MDA)中断传播，并行,管理发病病例。然而,人们已经看到，关于这最后一个支柱的文献和公共政策研究不足。在这项研究中,我们回顾了有关丝虫病发病率负担的文献和现有信息.此外,我们发现在美洲，在美洲，在发病援助方面实施结构化服务的情况很少。我们形成了一个综述，旨在评估发病机制，流行病学,影响,以及在淋巴丝虫病流行的美洲国家中丝虫病发病率的治疗。在PubMed上进行了结构化搜索，LILACS,Scopus,和WebofScience数据库没有时间和语言限制。三名评审员评估了2150项研究，并进行了数据提取，并通过对发现的研究进行评分来进行质量评估。关于丝虫病发病率负担的现有文献和现有信息，以及在美洲实施关于发病率援助的结构化服务，都被发现是稀缺的。现在已经确定了这个知识差距，卫生服务部门和研究人员都需要寻求实施和加强与发病支柱相关的GPELF策略的维护.
