Abstract：
The psychosocial impact of psoriasis is well documented. However, the contributing role of clinical disease characteristics is not satisfactorily explored. This study aimed to validate the Self-administered Psoriasis Area and Severity Index (SAPASI) to a Portuguese population (SAPASI-PT) and to perform its cross-validation, assessing how the results will generalize to an independent data set, with the Psoriasis Area and Severity Index (PASI), in order to assess the influence of psoriasis\' severity on psychosocial disability and psychopathology.
A cross-sectional study with 228 patients with psoriasis was carried out. Data was collected through a sociodemographic and clinical questionnaire, SAPASI-PT, the Psoriasis Disability Index (PDI) and the Brief Symptoms Inventory (BSI). The cultural and linguistic adaptation of SAPASI to a Portuguese version and the cross validation with PASI was carried out. Multiple associations between psychosocial disability, psychopathology and severity, discomfort and location of lesions were investigated through logistic regression models.
A good adjustment model for SAPASI-PT is found. Also, associations between psychosocial disability, psychopathology and the psoriasis severity and discomfort are found. The existence of lesions is positively associated with the severity of the disease. Patients with lesions in hands or genitals are those reporting a greater discomfort. The presence of lesions in hands is positively associated with PDI, i.e., with leisure and with treatment, marginally. Additionally, patients scoring higher in the personal dimension are found to have a significantly greater percentage of lesions in the genitals.
The psoriasis severity and location of lesions are important determinants of patients´ quality of life. Lesions on face, hands and genitals are associated with a higher impact on psychosocial wellbeing of patients. Psychological counselling should be considered within psoriasis treatment context in patients with the described disease manifestations.
A cross-sectional study with 228 patients with psoriasis was carried out. Data was collected through a sociodemographic and clinical questionnaire, SAPASI-PT, the Psoriasis Disability Index (PDI) and the Brief Symptoms Inventory (BSI). The cultural and linguistic adaptation of SAPASI to a Portuguese version and the cross validation with PASI was carried out. Multiple associations between psychosocial disability, psychopathology and severity, discomfort and location of lesions were investigated through logistic regression models.
A good adjustment model for SAPASI-PT is found. Also, associations between psychosocial disability, psychopathology and the psoriasis severity and discomfort are found. The existence of lesions is positively associated with the severity of the disease. Patients with lesions in hands or genitals are those reporting a greater discomfort. The presence of lesions in hands is positively associated with PDI, i.e., with leisure and with treatment, marginally. Additionally, patients scoring higher in the personal dimension are found to have a significantly greater percentage of lesions in the genitals.
The psoriasis severity and location of lesions are important determinants of patients´ quality of life. Lesions on face, hands and genitals are associated with a higher impact on psychosocial wellbeing of patients. Psychological counselling should be considered within psoriasis treatment context in patients with the described disease manifestations.
摘要：
牛皮癣的社会心理影响是有据可查的。然而,临床疾病特征的作用尚未得到令人满意的探索。本研究旨在验证自我管理的银屑病面积和严重程度指数（SAPASI）对葡萄牙人群（SAPASI-PT），并进行交叉验证，评估结果将如何推广到一个独立的数据集，与牛皮癣面积和严重程度指数（PASI），为了评估牛皮癣严重程度对心理社会残疾和精神病理学的影响。
对228名银屑病患者进行了横断面研究。数据是通过社会人口统计学和临床问卷收集的，SAPASI-PT,银屑病残疾指数(PDI)和简要症状量表(BSI)。进行了SAPASI对葡萄牙语版本的文化和语言适应，并与PASI进行了交叉验证。心理社会残疾之间的多重关联，精神病理学和严重性，通过logistic回归模型研究病变的不适和位置。
找到了SAPASI-PT的良好调整模型。此外，心理社会残疾之间的关联，精神病理学和牛皮癣的严重程度和不适被发现。病变的存在与疾病的严重程度呈正相关。手部或生殖器有病变的患者是那些报告有更大不适的患者。手部病变的存在与PDI呈正相关，即，休闲和治疗，边际上。此外,发现个人维度得分较高的患者生殖器病变比例明显较高.
银屑病的严重程度和病变部位是患者生活质量的重要决定因素。脸上有病变,手和生殖器对患者的心理健康有更高的影响。对于具有所述疾病表现的患者，应在牛皮癣治疗背景下考虑心理咨询。
对228名银屑病患者进行了横断面研究。数据是通过社会人口统计学和临床问卷收集的，SAPASI-PT,银屑病残疾指数(PDI)和简要症状量表(BSI)。进行了SAPASI对葡萄牙语版本的文化和语言适应，并与PASI进行了交叉验证。心理社会残疾之间的多重关联，精神病理学和严重性，通过logistic回归模型研究病变的不适和位置。
找到了SAPASI-PT的良好调整模型。此外，心理社会残疾之间的关联，精神病理学和牛皮癣的严重程度和不适被发现。病变的存在与疾病的严重程度呈正相关。手部或生殖器有病变的患者是那些报告有更大不适的患者。手部病变的存在与PDI呈正相关，即，休闲和治疗，边际上。此外,发现个人维度得分较高的患者生殖器病变比例明显较高.
银屑病的严重程度和病变部位是患者生活质量的重要决定因素。脸上有病变,手和生殖器对患者的心理健康有更高的影响。对于具有所述疾病表现的患者，应在牛皮癣治疗背景下考虑心理咨询。
