Abstract：
The Northern Territory (NT) of Australia is currently experiencing a syphilis epidemic. Neurosyphilis is commonly considered in the differential diagnosis for patients presenting with neurologic conditions such as dementia and stroke in the NT.
To explore the local epidemiologic, diagnostic and treatment complexities of neurosyphilis in the NT and produce a guideline for clinical practice.
A database search was undertaken and local and global neurosyphilis guidelines were analysed. A guideline was created based on findings of the critical review and consultation with local multidisciplinary experts.
Neurosyphilis is frequently encountered in the NT but studies suggest it is often undertreated. Dementia is the most common clinical presentation locally. Establishing a diagnosis of neurosyphilis is complex and requires stepwise evaluation of clinical, laboratory and radiological findings.
A clinical guideline and algorithm have been developed for the diagnosis and management of patients with neurosyphilis.
To explore the local epidemiologic, diagnostic and treatment complexities of neurosyphilis in the NT and produce a guideline for clinical practice.
A database search was undertaken and local and global neurosyphilis guidelines were analysed. A guideline was created based on findings of the critical review and consultation with local multidisciplinary experts.
Neurosyphilis is frequently encountered in the NT but studies suggest it is often undertreated. Dementia is the most common clinical presentation locally. Establishing a diagnosis of neurosyphilis is complex and requires stepwise evaluation of clinical, laboratory and radiological findings.
A clinical guideline and algorithm have been developed for the diagnosis and management of patients with neurosyphilis.
摘要：
背景：澳大利亚北领地（NT）目前正在经历梅毒流行。神经梅毒通常在NT中患有诸如痴呆和中风等神经系统疾病的患者的鉴别诊断中被考虑。
目的：探索当地流行病学，NT中神经梅毒的诊断和治疗复杂性，并为临床实践提供指导。
方法：进行了数据库搜索，并分析了本地和全球神经梅毒指南。根据关键审查的结果和与当地多学科专家的协商制定了指南。
结果：在NT中经常遇到神经梅毒，但研究表明，它通常没有得到充分治疗。痴呆是局部最常见的临床表现。建立神经梅毒的诊断是复杂的，需要逐步评估临床，实验室和放射学发现。
结论：已经为神经梅毒患者的诊断和治疗制定了临床指南和算法。
目的：探索当地流行病学，NT中神经梅毒的诊断和治疗复杂性，并为临床实践提供指导。
方法：进行了数据库搜索，并分析了本地和全球神经梅毒指南。根据关键审查的结果和与当地多学科专家的协商制定了指南。
结果：在NT中经常遇到神经梅毒，但研究表明，它通常没有得到充分治疗。痴呆是局部最常见的临床表现。建立神经梅毒的诊断是复杂的，需要逐步评估临床，实验室和放射学发现。
结论：已经为神经梅毒患者的诊断和治疗制定了临床指南和算法。
