Abstract:
Acanthamoeba keratitis (AK), the vision-threatening disease caused by the amphizoic, potentially parasitic amoebae is growing threat for public health in Poland and worldwide. The report presents the case of 70-year-old man with severe keratitis admitted to an Ophthalmology Clinic. Before admission, the patient had been treated for 6 months with antibacterial and antifungal drugs in other units, without improvement in the eye condition. The use of in vivo confocal microscopy and in vitro cultivation allowed diagnosis to be verified and AK successfully treated. Awareness of the threat to public health caused by Acanthamoeba spp is still insufficient. If there is failure in response to first line therapy, AK should be taken into account,despite the lack of identified risk factors. In vitro monitoring of amoebic strain can be helpful for prognosis of the course of the corneal disease. Improvement in duration from first symptoms until proper diagnosis is decisive for better treatment efficacy.
摘要:
棘阿米巴角膜炎(AK),由两栖动物引起的视力威胁疾病,潜在的寄生变形虫对波兰和全世界的公共健康的威胁越来越大。该报告介绍了眼科诊所收治的患有严重角膜炎的70岁男子的病例。入院前,该患者在其他单位接受了抗菌和抗真菌药物治疗6个月,没有改善眼部状况。使用体内共聚焦显微镜和体外培养可以验证诊断并成功治疗AK。对棘阿米巴对公众健康的威胁的认识仍然不足。如果一线治疗失败,AK应该被考虑在内,尽管缺乏确定的风险因素。阿米巴菌株的体外监测有助于角膜疾病病程的预后。从最初症状到正确诊断的持续时间的改善对于更好的治疗效果是决定性的。