关键词: COVID-19 biotechnology genetic modification model organism transgenesis

Mesh : COVID-19 / epidemiology virology SARS-CoV-2 / genetics Humans Animals Pandemics Gene Expression Regulation

来  源:   DOI:10.1089/dna.2021.0514   PDF(Pubmed)

Abstract:
The current pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected most of the world in a profound way. As an indirect consequence, the general public has been put into direct contact with the research process, almost in real time. Justifiably, a lot of this focus has been targeted toward research directly linked to coronavirus disease 2019 (COVID-19). In this opinion article, we want to highlight to a general audience the value of having a diverse \"portfolio\" of research approaches for society as a whole. In this study, we will focus on our field of research, namely the study of gene regulation through the use of transgenesis. We will highlight how this type of research can also be used to provide a better understanding as well as tools to fight SARS-CoV-2 and other future challenges.
摘要:
当前由严重急性呼吸道综合症冠状病毒2(SARS-CoV-2)引起的大流行已对世界大部分地区产生了深远的影响。作为一个间接的结果,公众已经直接接触了研究过程,几乎是实时的。合理的,很多焦点都针对与2019年冠状病毒病(COVID-19)直接相关的研究。在这篇观点文章中,我们想向普通观众强调,为整个社会提供多样化的“投资组合”研究方法的价值。在这项研究中,我们将专注于我们的研究领域,即通过使用转基因来研究基因调控。我们将重点介绍如何使用这种类型的研究来提供更好的理解以及应对SARS-CoV-2和其他未来挑战的工具。
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