Abstract：
OBJECTIVE: To compare the outcomes of phacoviscocanalostomy and viscocanalostomy in patients with primary open angle glaucoma.
METHODS: This non randomized, prospective comparative study included 168 eyes of 168 patients with primary open angle glaucoma (POAG). Phacoviscocanalostomy was performed in 94 eyes with POAG and cataract and viscocanalostomy was performed in 74 eyes with POAG. Preoperative and postoperative intraocular pressures (IOP), number of antiglaucoma medication, intraoperative and postoperative complications were recorded throughout the follow-up period.
RESULTS: The mean follow-up after surgery was 20.13 ± 7.9 months. Mean IOP decreased significantly 1 month after surgery in both groups (p < 0.001) and remained significantly lower from its preoperative value at all follow-up visits. The postoperative mean IOP at the last follow up in phacoviscocanalostomy and viscocanalostomy was 14.98 ± 4.8 mmHg and 16.84 ± 5.0 mmHg, respectively (p = 0.001). Complete success rate in phacoviscocanalostomy and viscocanalostomy groups was 83.1% and 56.8%, respectively (p = 0.008). Qualified success rate was achieved in 89.4% eyes in the phacoviscocanalostomy group and 83.8% of viscocanalostomy group (p = 0.534). The Best corrected visual acuity (BCVA) in phacoviscocanalostomy group improved significantly post-operatively (p = 0.001). Postoperative antiglaucoma medication in both groups were significantly less than the preoperative values (p = 0.001).
CONCLUSIONS: Both Phacoviscocanalostomy and viscocanalostmy are effective procedures in the control of IOP in patients with POAG with and without cataract. Higher complete success rates and BCVA were achieved in phacoviscocanalostomy. Therefore, phacoviscocanalostomy and viscocanalostomy are recommended in eyes with medically uncontrolled primary open-angle glaucoma with and without coexisting cataract.
METHODS: This non randomized, prospective comparative study included 168 eyes of 168 patients with primary open angle glaucoma (POAG). Phacoviscocanalostomy was performed in 94 eyes with POAG and cataract and viscocanalostomy was performed in 74 eyes with POAG. Preoperative and postoperative intraocular pressures (IOP), number of antiglaucoma medication, intraoperative and postoperative complications were recorded throughout the follow-up period.
RESULTS: The mean follow-up after surgery was 20.13 ± 7.9 months. Mean IOP decreased significantly 1 month after surgery in both groups (p < 0.001) and remained significantly lower from its preoperative value at all follow-up visits. The postoperative mean IOP at the last follow up in phacoviscocanalostomy and viscocanalostomy was 14.98 ± 4.8 mmHg and 16.84 ± 5.0 mmHg, respectively (p = 0.001). Complete success rate in phacoviscocanalostomy and viscocanalostomy groups was 83.1% and 56.8%, respectively (p = 0.008). Qualified success rate was achieved in 89.4% eyes in the phacoviscocanalostomy group and 83.8% of viscocanalostomy group (p = 0.534). The Best corrected visual acuity (BCVA) in phacoviscocanalostomy group improved significantly post-operatively (p = 0.001). Postoperative antiglaucoma medication in both groups were significantly less than the preoperative values (p = 0.001).
CONCLUSIONS: Both Phacoviscocanalostomy and viscocanalostmy are effective procedures in the control of IOP in patients with POAG with and without cataract. Higher complete success rates and BCVA were achieved in phacoviscocanalostomy. Therefore, phacoviscocanalostomy and viscocanalostomy are recommended in eyes with medically uncontrolled primary open-angle glaucoma with and without coexisting cataract.
摘要：
目的：比较原发性开角型青光眼患者行超声粘管造口术和超声粘管造口术的疗效。
方法：这种非随机，前瞻性比较研究纳入了168例原发性开角型青光眼(POAG)患者的168只眼.在94只眼的POAG和白内障中进行了声囊吻合术，在74只眼的POAG中进行了声囊吻合术。术前和术后眼压（IOP），抗青光眼药物的数量，在整个随访期间记录术中和术后并发症。
结果：术后平均随访时间为20.13±7.9个月。两组患者术后1个月的平均IOP均显著降低(p<0.001),且在所有随访中,平均IOP均显著低于其术前值。末次随访时，声囊吻合术和声囊吻合术的术后平均眼压为14.98±4.8mmHg和16.84±5.0mmHg，分别(p=0.001)。超声粘孔造口术和粘孔造口术组的完全成功率分别为83.1%和56.8%，分别(p=0.008)。超声粘孔造口术组89.4％的眼睛和粘孔造口术组83.8％的眼睛达到了合格的成功率（p=0.534）。超声粘孔造口术组的最佳矫正视力（BCVA）在术后显着提高（p=0.001）。两组术后抗青光眼药物均明显低于术前（p=0.001）。
结论：对于患有和不患有白内障的POAG患者，Phosoclikocanalalomaloscalomalstic和粘canalomy都是控制IOP的有效方法。在超声粘孔造口术中获得了更高的完全成功率和BCVA。因此,对于医学上未控制的原发性开角型青光眼伴或不伴白内障的患者，建议行超声粘管造口术和粘管造口术。
方法：这种非随机，前瞻性比较研究纳入了168例原发性开角型青光眼(POAG)患者的168只眼.在94只眼的POAG和白内障中进行了声囊吻合术，在74只眼的POAG中进行了声囊吻合术。术前和术后眼压（IOP），抗青光眼药物的数量，在整个随访期间记录术中和术后并发症。
结果：术后平均随访时间为20.13±7.9个月。两组患者术后1个月的平均IOP均显著降低(p<0.001),且在所有随访中,平均IOP均显著低于其术前值。末次随访时，声囊吻合术和声囊吻合术的术后平均眼压为14.98±4.8mmHg和16.84±5.0mmHg，分别(p=0.001)。超声粘孔造口术和粘孔造口术组的完全成功率分别为83.1%和56.8%，分别(p=0.008)。超声粘孔造口术组89.4％的眼睛和粘孔造口术组83.8％的眼睛达到了合格的成功率（p=0.534）。超声粘孔造口术组的最佳矫正视力（BCVA）在术后显着提高（p=0.001）。两组术后抗青光眼药物均明显低于术前（p=0.001）。
结论：对于患有和不患有白内障的POAG患者，Phosoclikocanalalomaloscalomalstic和粘canalomy都是控制IOP的有效方法。在超声粘孔造口术中获得了更高的完全成功率和BCVA。因此,对于医学上未控制的原发性开角型青光眼伴或不伴白内障的患者，建议行超声粘管造口术和粘管造口术。
