间充质干细胞通过线粒体信号通路对过敏性哮喘的免疫调节作用.
关键词: AHR, Airway hyperresponsiveness ATP, Adenosine triphosphate Allergy BALF, Bronchoalveolar lavage fluid BM, Bone marrow CCL, Chemokine (C-C motif) ligand CD, Cluster of differentiation COX, Cyclooxygenase Cys-LT, Cysteinyl Leukotriene Cytb, Cytochrome b Drp1, Mitochondrial fission depends on the cytosolic GTPase dynamin-related protein 1 ELISA, Enzyme-linked immunosorbent assay FIS1, Mitochondrial fission 1 protein H&E, Haemotoxylin and eosin HGF, Hepatocyte growth factor HLA, Human leukocyte antigen HO, Heme oxygenase IDO, Indoleamine 2,3-dioxygenase IFN, Interferon IL, Interleukin IP, Intraperitoneal injection IT, Intratrachea administration Ig, Immunoglobulin Immune system Inflammation LT, Leukotriene MFN, Mitofusin MIP, macrophage inflammatory protein MMP, Matrix metalloproteinase MSC MSC, mesenchymal stem cell MSC/BI, mesenchymal stem cell bronchial administration MSC/IV, mesenchymal stem cell intravenous injection ND1, NADH-ubiquinone oxidoreductase chain 1 NO, Nitric oxide Nrf, Nuclear erythroid 2 p45-related factor OPA1, Mitochondrial dynamin like GTPase OVA, Ovalbumin PAS, Periodic-acid-Schiff PBS, Phosphate-buffered saline PGC1a, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha PGE2, Prostaglandin E2 ROS, Reactive oxygen species TFAM, Transcription factor A mitochondrial TGF, Transforming growth factor TNF, Tumor necrosis factor Th, T helper iPSC, induced pluripotent stem cells
来 源: DOI:10.1016/j.sjbs.2021.07.071 PDF(Pubmed)