MiR - 185 - 5p 通过抑制 GPX1 抑制急性髓细胞性白血病。
关键词: Acute myeloid leukemia Differentiation GPX1 Migration Proliferation miR-185-5p
Mesh : Animals Apoptosis Case-Control Studies Cell Differentiation Cell Movement Cell Proliferation Disease Progression Gene Expression Regulation, Enzymologic Gene Expression Regulation, Leukemic Glutathione Peroxidase / genetics metabolism HL-60 Cells Humans Leukemia, Myeloid, Acute / enzymology genetics pathology prevention & control Mice, Inbred BALB C Mice, Nude MicroRNAs / genetics metabolism Neoplasm Invasiveness RNA Interference Signal Transduction Glutathione Peroxidase GPX1 Mice
来 源: DOI:10.1016/j.mvr.2021.104296