PDF(Pubmed)
Abstract：
Scleroderma-like disorders include a set of entities involving cutis, subcutis and, sometimes, even muscular tissue, caused by several pathogenetic mechanisms responsible for different clinical-pathological pictures. The absence of antinuclear antibodies (ANA), Raynaud\'s phenomenon and capillaroscopic anomalies constitutes an important element of differential diagnosis with systemic sclerosis. When scleroderma can be excluded, on the basis of the main body sites, clinical evolution, any associated pathological conditions and specific histological features, it is possible to make a correct diagnosis.
摘要：
硬皮病样疾病包括一组涉及皮肤的实体，皮下组织和,有时,甚至肌肉组织，由负责不同临床病理图片的几种致病机制引起。抗核抗体（ANA）的缺失，雷诺现象和毛细血管镜异常是鉴别诊断系统性硬化症的重要因素。当硬皮病可以排除时，根据主体站点，临床进化，任何相关的病理状况和特定的组织学特征，做出正确的诊断是可能的。
