Prenatal Diagnosis and Outcome of Tracheal Agenesis as Part of Congenital High Airway Obstruction Syndrome. Case Presentation and Literature Review.

• 影响指数: 2.948
• 发表时间: Nov 2021 16
• 来源期刊: Medicina (Kaunas)
• DOI: 10.3390/medicina57111253
• PMID: 34833471
• 文章类型: Case Reports
• 中科院分区: Q3
• 方向: 医学
• 作者列表: Georgescu T,Radoi V,Radulescu M,Ilian A,Toader OD,Pop LG,Bacalbasa N

关键词: fetal demise; hydrops; tracheal atresia

Mesh: Airway Obstruction / diagnostic imaging etiology; Constriction, Pathologic; Female; Humans; Male; Pregnancy; Prenatal Diagnosis; Trachea / abnormalities diagnostic imaging; Ultrasonography, Prenatal

Abstract

Tracheal atresia is an extremely rare condition whereby a partial or total obstruction of the trachea is seen. It is almost always lethal, with just a handful of cases that ended with a good outcome. In this study we report on a 15-week male fetus, diagnosed with hyperechogenic lungs, midline heart position and inverted diaphragm. Sonographic findings suggest congenital High Airway Obstruction Syndrome (CHAOS) An ultrasound scan and fetal MRI were not able to point out the exact obstruction level. In spite of extensive counselling, the parents opted to carry on with the pregnancy. Fetal demise was noted on a scan at 19 weeks gestation. After the elective termination of pregnancy, a post-mortem examination showed partial tracheal atresia with no other anomalies. Despite technological progress in CHAOS syndrome, a precise diagnosis and accurate prognosis remain elusive.