PDF(Pubmed)
Abstract：
Yellow hair discoloration (xanthotrichia) has been observed in several settings. Indeed, acquired xanthotrichia, in addition to environmental and occupational causes, can be observed secondary to either iatrogenic, topical, or systemic exposure to systemic drugs and certain systemic conditions: most commonly essential fatty acid deficiencies, protein deficiency, or vitamin B12 deficiency. Smoker\'s mustache refers to the acquired yellow discoloration of previously white hair on the cutaneous upper lip of men. These individuals are typically elderly and have a history of smoking either cigarettes, cigars, or pipes of several years\' duration. The asymptomatic dyschromia often originates centrally, affecting the hair overlying the philtrum and expanding laterally. The condition is asymptomatic, and affected individuals are either unaware of the color change or not concerned with their altered appearance. Yellow to brown discoloration of the thumbnails, fingernails, or both (such as nicotine sign and/or harlequin nails) may be an accompanying clinical stigma to the smoker\'s mustache and a clue to the diagnosis. Management options include smoking cessation or hair removal of the discolored hair, or both; however, patients usually elect to continue smoking, maintain their facial hair, and continue to display their distinctive yellow smoker\'s mustache.
摘要：
在几种情况下观察到黄色头发变色（黄色发丝）。的确,获得的黄腐病,除了环境和职业原因，可以观察到继发于医源性，topic,或全身暴露于全身药物和某些全身状况：最常见的必需脂肪酸缺乏，蛋白质缺乏，或维生素B12缺乏。吸烟者的胡子是指男性皮肤上唇上先前白发的黄色变色。这些人通常是老年人，有吸烟史，雪茄,或几年的管道。无症状的色素异常通常起源于中央，影响毛发覆盖人的毛发并横向扩张。病情是无症状的,受影响的个体要么不知道颜色变化，要么不关心他们的外观改变。缩略图的黄色到棕色变色，手指甲,或两者（如尼古丁标志和/或丑角指甲）可能是吸烟者胡子的伴随临床污名和诊断线索。管理选项包括戒烟或去除变色的头发，或两者;然而,患者通常选择继续吸烟，保持他们的面部毛发，并继续展示他们独特的黄色吸烟者的胡子。
