关键词: bone union bone volume mandibular defects osteocutaneous radial forearm free flap squamous cell carcinoma

Mesh : Carcinoma, Squamous Cell / surgery Forearm / surgery Free Tissue Flaps / surgery Humans Mandible / surgery Mandibular Reconstruction Radius / surgery Plastic Surgery Procedures Retrospective Studies

来  源:   DOI:10.1002/hed.26939

Abstract:
Historical concerns over bone resorption and malunion of the osteocutaneous radial forearm free flap (OCRFFF) limited its widespread adoption for head and neck reconstruction, despite lack of outcomes data evaluating this notion.
A retrospective cohort study was performed including patients 18 years or older who underwent reconstruction of the mandible using an OCRFFF. Linear modeling and logistic regression were used to evaluate the change in bone volume and union over time.
One hundred and twenty-one patients were included in the study. A mixed effects linear model incorporating age, sex, treatment type, and number of bone segments did not demonstrate a significant loss of bone volume over time. A logistic regression model identified lack of adjuvant treatment and time to be significantly associated with complete union.
This study supports that the OCRFFF is a stable form of osseus reconstruction for defects of the head and neck.
摘要:
对骨皮肤radial前臂游离皮瓣(OCRFFF)的骨吸收和畸形愈合的历史关注限制了其在头颈部重建中的广泛采用,尽管缺乏评估这一概念的结果数据。
进行了一项回顾性队列研究,包括18岁或以上使用OCRFFF进行下颌骨重建的患者。使用线性建模和逻辑回归来评估骨体积和愈合随时间的变化。
研究中纳入了121名患者。一个包含年龄的混合效应线性模型,性别,治疗类型,骨段和骨段的数量没有显示出随着时间的推移骨体积的显著损失。逻辑回归模型确定缺乏辅助治疗和时间与完全结合显着相关。
这项研究支持OCRFFF是一种稳定的骨重建形式,用于治疗头颈部的缺损。
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