A literature search following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and using searching terms related to esthetic and reconstructive breast surgery was conducted across three databases: PubMed, Scopus and Google Scholar. Included articles were analyzed to extract data points of interest including patient age, type of surgery, organ transplanted, underlying conditions associated with organ transplantation, follow-up, immunosuppressive drugs and their side effects, perioperative management and complications related to the breast plastic procedures in SOT recipients.
A total of 1,298 articles were retrieved from the mentioned electronic databases. Eight full articles were finally included in this systematic review. In these articles, a total of 41 cases of breast plastic surgery after solid organ transplantation were reported. Procedures were esthetic in nature in 26.83% of cases (11 of 41 cases) and reconstructive in 73.17% of them (30 of 41 cases). No deaths were reported.
Although esthetic and reconstructive breast surgery could be performed safely in SOT recipients, the dosage of immunosuppression and patient's overall health status with regard to the length and extent of the planned procedure should always be taken into account. From the literature data analysis, it is not possible to draw a statistical conclusion that the complication rate of surgery in immunosuppressed post-transplant patients is the same as in normal, not immunosuppressed population. Further and more valid clinical studies are warranted.
在以下三个数据库中进行了文献检索:PubMed,Scopus和谷歌学者。对纳入的文章进行分析,以提取感兴趣的数据点,包括患者年龄,手术类型,器官移植,与器官移植相关的潜在条件,后续行动,免疫抑制药物及其副作用,SOT受者的围手术期处理和与乳房整形手术相关的并发症。
从上述电子数据库中检索到总共1,298篇文章。本系统综述最终纳入了8篇完整文章。在这些文章中,共报告41例实体器官移植后乳房整形手术。26.83%的病例(41例中的11例)具有美学性质,73.17%的病例(41例中的30例)具有重建性质。没有死亡报告。
尽管可以安全地在SOT接受者中进行美学和重建乳房手术,免疫抑制剂的剂量和患者的整体健康状态与计划程序的长度和程度应始终考虑在内。从文献数据分析来看,无法得出免疫抑制移植后患者手术并发症发生率与正常人相同的统计结论,不是免疫抑制人群。进一步和更有效的临床研究是必要的。