Abstract：
Country- and ethnicity-specific reference values for echocardiographic parameters are necessary for decision making. No prior studies have examined reference values in adults from the Amazon Basin of Brazil. We performed echocardiographic examinations in 290 healthy adults (mean age 37 ± 14 years, 40% male) from the Brazilian Amazon. Left ventricular (LV) dimensions and volumes were obtained and indexed to body surface area. We also assessed systolic (LV ejection fraction [LVEF] and global longitudinal strain [GLS]) and diastolic function. LV dimensions and volumes were larger in males compared to females, but after indexation only volumes remained larger (P < 0.001 for all). Parameters of systolic function, were significantly greater in females (LVEF 50 to 68%, GLS - 17 to - 24%) than in males (LVEF 50 to 67%, GLS - 15 to - 23%, P < 0.05). Upper limits of normality for cardiac dimensions (indexed and non-indexed) were markedly higher compared to contemporary guidelines (American Society of Echocardiography) and the Brazilian subgroup in the World Alliance Society of Echocardiography (WASE). Lower limit of normality for LVEF (both sex 50%) and upper limit of normality for the left atrial volume index (LAVI) (male: 31 mL/m2, female: 25 mL/m2) were within normal range but slightly lower compared to guidelines and the WASE study. Other diastolic parameters, including E/A-ratio, E/e\' ratio and peak tricuspid regurgitation velocity were compatible with present recommendations. Normal reference ranges of echocardiographic parameters in healthy adults from the Brazilian Amazon Basin may be different compared to international guidelines and data from other regions of Brazil. This applies specifically for LVEF and LAVI.
摘要：
超声心动图参数的特定于国家和种族的参考值对于决策是必要的。以前没有研究检查过巴西亚马逊河流域成年人的参考值。我们对290名健康成年人进行了超声心动图检查（平均年龄37±14岁，40％的男性）来自巴西亚马逊。获得左心室（LV）尺寸和体积，并将其索引到体表面积。我们还评估了收缩期（左心室射血分数[LVEF]和整体纵向应变[GLS]）和舒张功能。男性的LV尺寸和体积大于女性，但指数化后，只有体积保持较大（全部P<0.001）。心脏收缩功能的参数,在女性中显著更大(LVEF为50％至68％，GLS-17至-24%）比男性(LVEF50至67%，GLS-15至-23%，P<0.05)。与当代指南（美国超声心动图协会）和世界超声心动图联盟协会（WASE）的巴西亚组相比，心脏尺寸（索引和非索引）的正常性上限明显更高。LVEF的正常值下限（两种性别均为50％）和左心房容积指数（LAVI）的正常值上限（男性：31mL/m2，女性：25mL/m2）在正常范围内，但略低于指南和WASE研究。其他舒张参数，包括E/A比，E/e比值和三尖瓣反流峰值速度符合目前的建议。与国际指南和巴西其他地区的数据相比，巴西亚马逊盆地健康成年人的超声心动图参数的正常参考范围可能有所不同。这特别适用于LVEF和LAVI。
