Abstract：
Massoia lactone could be released from liamocins produced by Aureobasidium melanogenum M39. The obtained Massoia lactone was very stable and highly active against many fungal crop pathogens which cause many plant diseases and food unsafety. Massoia lactone treatment not only could effectively inhibit their hyphal growth and spore germination, but also caused pore formation in cell membrane, reduction of ergosterol content, rise in intracellular ROS levels, and leakage of intracellular components, consequently leading to cellular necrosis and cell death. The direct contact of Massoia lactone with Fusarium graminearum spores could stop the development of Fusarium head blight symptom in the diseased wheats. Therefore, Massoia lactone could be a promising candidate for development as an effective and green bio-fungicide because of its high anti-fungal activity and the multiplicity of mode of its action.
摘要：
马苏虫内酯可以从黑色素梭菌M39产生的美洲霉素中释放。所获得的马苏内酯对许多引起许多植物病害和食品不安全的真菌作物病原体非常稳定且具有高度活性。马苏内酯处理不仅能有效抑制其菌丝生长和孢子萌发,但也导致细胞膜上的孔形成，麦角甾醇含量的减少，细胞内ROS水平升高，和细胞内成分的泄漏，从而导致细胞坏死和细胞死亡。马苏内酯与镰刀菌孢子的直接接触可以阻止患病小麦中镰刀菌枯萎病症状的发展。因此,马苏内酯由于其高抗真菌活性和多种作用方式，可能是开发为有效和绿色生物杀菌剂的有希望的候选者。
