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Abstract：
BACKGROUND: In 2017, the American College of Cardiology/American Heart Association revised guidelines for diagnosis and management of hypertension in adults. The regional impact of the updated guidelines on the prevalence of hypertension in India is unknown.
METHODS: Data from nationally representative Indian households were analyzed to estimate the regional prevalence of hypertension according to the old and the new guidelines in men (age 18-54 years) and women (age 18-49 years). The old guidelines defined hypertension as a systolic blood pressure of ≥140 mmHg or diastolic blood pressure of ≥90 mmHg or treatment. The new guidelines define hypertension as a systolic blood pressure of ≥130 mmHg or diastolic blood pressure of ≥80 mmHg or treatment. We calculated the increase in the prevalence of hypertension among the states and union territories of India (hereafter \"states\").
RESULTS: Among 679,712 participants (85.6% women), the median age was 31 years (interquartile range 24, 40) and was comparable among men and women (33 vs. 31 years, respectively). The overall weighted prevalence according to old and new guidelines was 18.5% (95% CI 18.2, 18.7) and 43.0% (95% CI 42.8, 43.3), respectively. There was a significant increase in hypertension prevalence, both among men and women, and across all regions. The northeast region of the country had the highest prevalence.
CONCLUSIONS: The overall prevalence of hypertension significantly increases with the new compared to the old guidelines, however, the regional heterogeneity of prevalence of hypertension is maintained.
METHODS: Data from nationally representative Indian households were analyzed to estimate the regional prevalence of hypertension according to the old and the new guidelines in men (age 18-54 years) and women (age 18-49 years). The old guidelines defined hypertension as a systolic blood pressure of ≥140 mmHg or diastolic blood pressure of ≥90 mmHg or treatment. The new guidelines define hypertension as a systolic blood pressure of ≥130 mmHg or diastolic blood pressure of ≥80 mmHg or treatment. We calculated the increase in the prevalence of hypertension among the states and union territories of India (hereafter \"states\").
RESULTS: Among 679,712 participants (85.6% women), the median age was 31 years (interquartile range 24, 40) and was comparable among men and women (33 vs. 31 years, respectively). The overall weighted prevalence according to old and new guidelines was 18.5% (95% CI 18.2, 18.7) and 43.0% (95% CI 42.8, 43.3), respectively. There was a significant increase in hypertension prevalence, both among men and women, and across all regions. The northeast region of the country had the highest prevalence.
CONCLUSIONS: The overall prevalence of hypertension significantly increases with the new compared to the old guidelines, however, the regional heterogeneity of prevalence of hypertension is maintained.
摘要：
背景：2017年，美国心脏病学会/美国心脏协会修订了成人高血压诊断和管理指南。更新指南对印度高血压患病率的区域影响尚不清楚。
方法：分析了具有全国代表性的印度家庭的数据，以根据新旧指南在男性（18-54岁）和女性（18-49岁）中估计高血压的地区患病率。旧的指南将高血压定义为收缩压≥140mmHg或舒张压≥90mmHg或治疗。新指南将高血压定义为收缩压≥130mmHg或舒张压≥80mmHg或治疗。我们计算了印度各州和联邦地区（以下简称“州”）中高血压患病率的增加。
结果：在679,712名参与者（85.6％的女性）中，平均年龄为31岁(四分位距24,40)，男性和女性之间相当(33vs.31年,分别)。根据新旧指南，总体加权患病率为18.5%(95%CI18.2,18.7)和43.0%(95%CI42.8,43.3)，分别。高血压患病率显着增加，在男人和女人中，在所有地区。该国东北地区的患病率最高。
结论：与旧指南相比，新指南的高血压总体患病率显著增加，然而,高血压患病率的区域异质性得以维持.
方法：分析了具有全国代表性的印度家庭的数据，以根据新旧指南在男性（18-54岁）和女性（18-49岁）中估计高血压的地区患病率。旧的指南将高血压定义为收缩压≥140mmHg或舒张压≥90mmHg或治疗。新指南将高血压定义为收缩压≥130mmHg或舒张压≥80mmHg或治疗。我们计算了印度各州和联邦地区（以下简称“州”）中高血压患病率的增加。
结果：在679,712名参与者（85.6％的女性）中，平均年龄为31岁(四分位距24,40)，男性和女性之间相当(33vs.31年,分别)。根据新旧指南，总体加权患病率为18.5%(95%CI18.2,18.7)和43.0%(95%CI42.8,43.3)，分别。高血压患病率显着增加，在男人和女人中，在所有地区。该国东北地区的患病率最高。
结论：与旧指南相比，新指南的高血压总体患病率显著增加，然而,高血压患病率的区域异质性得以维持.
