ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary conditions, candidate evaluation, selection criteria, and pathology statements.

ISHLT 关于结缔组织病患者肺移植的共识文件 ： 第一部分 ： 流行病学 ，评估肺外状况 ，候选人评价,选择标准 ，和病理学陈述。

• 影响指数: 13.569
• 发表时间: 11 2021
• 来源期刊: J Heart Lung Transplant
• DOI: 10.1016/j.healun.2021.07.014
• PMID: 34417111
• 文章类型: Practice Guideline
• 中科院分区: Q1
• 方向: 医学
• 作者列表: Crespo MM,Lease ED,Sole A,Sandorfi N,Snyder LD,Berry GJ,Pavec JL,Venado AE,Cifrian JM,Goldberg H,Dilling DF,Gries C,Nair A,Willie K,Meyer KC,Shah RJ,Tokman S,Holm A,Patterson CM,McWilliams T,Shtraichman O,Bemiss B,Salgado J,Farver C,Strah H,Wassilew K,Kaza V,Howsare M,Murray M,Bhorade S,Budev M

关键词: connective tissue diseases; consensus statement; extrapulmonary conditions; lung transplantation; transplant candidacy criteria; transplant evaluation

Abstract

Patients with connective tissue disease (CTD) and advanced lung disease are often considered suboptimal candidates for lung transplantation (LTx) due to their underlying medical complexity and potential surgical risk. There is substantial variability across LTx centers regarding the evaluation and listing of these patients. The International Society for Heart and Lung Transplantation-supported consensus document on lung transplantation in patients with CTD standardization aims to clarify definitions of each disease state included under the term CTD, to describe the extrapulmonary manifestations of each disease requiring consideration before transplantation, and to outline the absolute contraindications to transplantation allowing risk stratification during the evaluation and selection of candidates for LTx.

摘要

结缔组织病（CTD）和晚期肺病患者由于其潜在的医学复杂性和潜在的手术风险，通常被认为是肺移植（LTx）的次优候选者。关于这些患者的评估和列表，LTx中心之间存在很大差异。国际心肺移植学会支持的关于CTD标准化患者肺移植的共识文件旨在阐明术语CTD下包括的每种疾病状态的定义。描述移植前需要考虑的每种疾病的肺外表现，并概述移植的绝对禁忌症，允许在评估和选择LTx候选人期间进行风险分层。