PDF(Sci-hub)
Abstract：
UNASSIGNED: Racial variation exists in the incidence of orofacial granulomatosis (OFG). The epidemiology and clinical characteristics of OFG in Asian countries are poorly described.
UNASSIGNED: To describe the epidemiologic and clinical features of OFG in China from data collected on chronic odontogenic infection and studied in actual practice regarding the long-term outcome of OFG patients receiving different treatments.
UNASSIGNED: Data on demographics, medical history, chronic odontogenic infection, and the extent of disease were collected, and long-term outcomes after the end of treatments were evaluated.
UNASSIGNED: Of the 165 OFG patients, 118 (71.5%; 95% CI 64.6%-78.5%) had a chronic odontogenic infection. There was a variety of difference between OFG with and without chronic odontogenic infection. Approximately 98.3% (95% confidence interval 94.8%-100%) of OFG patients with chronic odontogenic infection who received dental treatment showed a marked response, of whom 31 patients (53.4%; 95% confidence interval 40.2%-66.7%) had complete remission.
UNASSIGNED: Endoscopic investigations were not performed for most of the patients, and more detailed data were not collected, which might have demonstrated additional systemic problems.
UNASSIGNED: OFG with chronic odontogenic infection is the major clinical pattern of OFG in China, which may be a subtype of OFG. Dental treatment should necessarily be the preferred first-line therapy for such patients.
UNASSIGNED: To describe the epidemiologic and clinical features of OFG in China from data collected on chronic odontogenic infection and studied in actual practice regarding the long-term outcome of OFG patients receiving different treatments.
UNASSIGNED: Data on demographics, medical history, chronic odontogenic infection, and the extent of disease were collected, and long-term outcomes after the end of treatments were evaluated.
UNASSIGNED: Of the 165 OFG patients, 118 (71.5%; 95% CI 64.6%-78.5%) had a chronic odontogenic infection. There was a variety of difference between OFG with and without chronic odontogenic infection. Approximately 98.3% (95% confidence interval 94.8%-100%) of OFG patients with chronic odontogenic infection who received dental treatment showed a marked response, of whom 31 patients (53.4%; 95% confidence interval 40.2%-66.7%) had complete remission.
UNASSIGNED: Endoscopic investigations were not performed for most of the patients, and more detailed data were not collected, which might have demonstrated additional systemic problems.
UNASSIGNED: OFG with chronic odontogenic infection is the major clinical pattern of OFG in China, which may be a subtype of OFG. Dental treatment should necessarily be the preferred first-line therapy for such patients.
摘要：
■口面部肉芽肿病（OFG）的发病率存在种族差异。亚洲国家OFG的流行病学和临床特征描述不充分。
■从收集的慢性牙源性感染数据中描述中国OFG的流行病学和临床特征，并在实际实践中研究OFG患者接受不同治疗的长期结局。
■人口统计数据，病史,慢性牙源性感染，收集疾病的程度，并评估治疗结束后的长期结局.
■在165名OFG患者中，118（71.5％；95％CI64.6％-78.5％）患有慢性牙源性感染。有和没有慢性牙源性感染的OFG之间存在多种差异。大约98.3％（95％置信区间94.8％-100％）的OFG慢性牙源性感染患者接受牙科治疗后表现出明显的反应，其中31例(53.4%;95%置信区间40.2%-66.7%)完全缓解.
■大多数患者未进行内窥镜检查，没有收集更详细的数据，这可能证明了额外的系统性问题。
■OFG伴慢性牙源性感染是中国OFG的主要临床模式，这可能是OFG的一个亚型。牙科治疗必然是此类患者的首选一线治疗。
■从收集的慢性牙源性感染数据中描述中国OFG的流行病学和临床特征，并在实际实践中研究OFG患者接受不同治疗的长期结局。
■人口统计数据，病史,慢性牙源性感染，收集疾病的程度，并评估治疗结束后的长期结局.
■在165名OFG患者中，118（71.5％；95％CI64.6％-78.5％）患有慢性牙源性感染。有和没有慢性牙源性感染的OFG之间存在多种差异。大约98.3％（95％置信区间94.8％-100％）的OFG慢性牙源性感染患者接受牙科治疗后表现出明显的反应，其中31例(53.4%;95%置信区间40.2%-66.7%)完全缓解.
■大多数患者未进行内窥镜检查，没有收集更详细的数据，这可能证明了额外的系统性问题。
■OFG伴慢性牙源性感染是中国OFG的主要临床模式，这可能是OFG的一个亚型。牙科治疗必然是此类患者的首选一线治疗。
