关键词: Adjuvant Radiotherapy Radiothérapie Rattrapage Salvage

Mesh : Clinical Trials, Phase III as Topic Humans Lymphatic Irradiation Male Neoplasm Recurrence, Local Pelvis Postoperative Care Practice Guidelines as Topic Prostatectomy Prostatic Neoplasms / radiotherapy surgery Radiation Dose Hypofractionation Radiotherapy Dosage Radiotherapy, Adjuvant / methods standards Randomized Controlled Trials as Topic Salvage Therapy / methods

来  源:   DOI:10.1016/j.canrad.2021.07.003   PDF(Sci-hub)

Abstract:
Approximately thirty percent of patients experience biochemical recurrence after radical prostatectomy for prostate cancer. Early salvage radiotherapy has recently become a standard of care in this setting. The purpose of this review is first to summarize current knowledge in terms of dose to the prostate bed in light of the recent SAKK 09/10 randomized phase III trial results. The evidence on moderate hypofractionation will also be discussed whereas extreme hypofractionation remains highly investigational. Regarding target volumes, several different guidelines have been published to address the need for standardization of postoperative target delineation. The recent GFRU (Groupe Francophone de Radiothérapie Urologique) recommendations could represent an international consensus.
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