关键词: Children Crimean-Congo hemorrhagic fever Pediatric intensive care Ribavirin Therapeutic plasma exchange

来  源:   DOI:10.1016/j.transci.2021.103215   PDF(Sci-hub)

Abstract:
Crimean-Congo hemorrhagic fever (CCHF) is a life-threatening tick-borne viral infection. The most important step in the treatment of CCHF is supportive therapy. Ribavirin is the recommended antiviral agent for infected patients. We present a case of a child who presented to our pediatric intensive care unit due to CCHF and was treated with plasmapheresis and ribavirin. A previously healthy seven-month-old male infant presented to the emergency room with a fever of 39.5 °C, nosebleed, cough, vomiting, and weakness. We decided to apply plasmapheresis treatment due to multiple organ failure associated with thrombocytopenia, acute liver failure, and a family history of death from the disease. Plasmapheresis was performed in three sessions. By the sixth day of his admission to the intensive care unit, the patient\'s clinical condition had improved and his laboratory values had returned to normal, so he was transferred to the infectious diseases service in stable condition.
摘要:
克里米亚-刚果出血热(CCHF)是一种威胁生命的蜱传病毒感染。治疗CCHF最重要的步骤是支持治疗。利巴韦林是感染患者的推荐抗病毒药物。我们介绍了一例儿童,该儿童因CCHF而被送往儿科重症监护病房,并接受了血浆置换和利巴韦林治疗。一名先前健康的七个月大男婴因发烧39.5摄氏度而被送往急诊室,流鼻血,咳嗽,呕吐,和弱点。由于与血小板减少相关的多器官功能衰竭,我们决定应用血浆置换治疗。急性肝功能衰竭,和家族死于这种疾病的病史.分三次进行血浆置换。在他进入重症监护室的第六天,患者的临床状况有所改善,他的实验室值恢复正常,所以他被转移到传染病服务处,情况稳定。
公众号