Cardiac Amyloidosis: The Importance of Surveillance in a Patient With an Initial Negative Cardiac Biopsy.

心脏淀粉样变性 ： 在最初心脏活检阴性的患者中监测的重要性。

• 发表时间: Feb 2020
• 来源期刊: JACC Case Rep
• DOI: 10.1016/j.jaccas.2019.11.041
• PMID: 34317223
• 文章类型: Case Reports
• 作者列表: Ananthakrishna R,Lloyd R,Kuss BJ,Selvanayagam JB

关键词: AL, light-chain; ATTR, transthyretin; CA, cardiac amyloidosis; CMR, cardiac magnetic resonance; ECV, extracellular volume; MGUS, monoclonal gammopathy of unknown significance; NT-proBNP, N-terminal pro-B-type natriuretic peptide; amyloidosis; biopsy; cardiac magnetic resonance

Abstract

Cardiac amyloidosis is a progressive disorder and is sometimes difficult to diagnose even when suspected in the appropriate clinical setting. We present an interesting case of rapidly progressive light-chain cardiac amyloidosis and highlights the importance of close monitoring even when the initial biopsy and imaging findings are not pathognomonic for amyloidosis. (Level of Difficulty: Beginner.).

摘要

心脏淀粉样变性是一种进行性疾病，即使在适当的临床环境中怀疑，有时也难以诊断。我们提出了一个有趣的快速进行性轻链心脏淀粉样变性病例，并强调了密切监测的重要性，即使最初的活检和影像学发现不是淀粉样变性的致病标志。（难度等级：初学者。).