UNASSIGNED: A 64-year-old male patient presented with a history of 1 month of gross haematuria and 3 months of left flank pain. CT urography revealed a soft tissue mass in the upper ureter, which was slightly enhanced on contrast-enhanced CT. Nephroureterectomy was performed after the patient was diagnosed with a tumour in the left ureter. Microscopy and immunohistochemical examination confirmed the mass to be a SCNEC collision with SCC. Two months after the surgery, the patient received adjuvant chemotherapy (cisplatin/etoposide). After 14 months of follow-up, no local recurrence or distant metastasis was found.
UNASSIGNED: Ureteral collision carcinoma with SCNEC predominantly occurs in Asian individuals, is difficult to diagnose preoperatively and is highly invasive. The current management of ureteral collision carcinoma is a comprehensive treatment based on surgery.
■一名64岁男性患者,有1个月的肉眼血尿和3个月的左侧腹疼痛病史。CT尿路造影显示输尿管上段有软组织肿块,在对比增强CT上略有增强。在患者被诊断出患有左输尿管肿瘤后,进行了肾输尿管切除术。显微镜和免疫组织化学检查证实肿块是SCNEC与SCC碰撞。手术后两个月,患者接受辅助化疗(顺铂/依托泊苷).经过14个月的随访,未发现局部复发或远处转移。
■伴有SCNEC的输尿管碰撞癌主要发生在亚洲个体,术前难以诊断,并且具有很强的侵入性。目前输尿管碰撞癌的治疗是以手术为主的综合治疗。