PDF(Pubmed)
Abstract：
UNASSIGNED: Small cell neuroendocrine carcinoma (SCNEC) of the ureter is a rare tumour, accounting for less than 0.5% of all ureteral tumours. SCNEC tumours are highly aggressive and patients have a poor prognosis. Ureteral SCNEC colliding with other pathological types of tumours is extremely rare. In this paper, we present the case of a patient with ureteral small cell carcinoma colliding with squamous cell carcinoma and review the literature regarding the clinicopathological features, treatment and prognosis of thus tumour. To the best of our knowledge, this is the second identified case of ureteral SCNEC colliding with SCC.
UNASSIGNED: A 64-year-old male patient presented with a history of 1 month of gross haematuria and 3 months of left flank pain. CT urography revealed a soft tissue mass in the upper ureter, which was slightly enhanced on contrast-enhanced CT. Nephroureterectomy was performed after the patient was diagnosed with a tumour in the left ureter. Microscopy and immunohistochemical examination confirmed the mass to be a SCNEC collision with SCC. Two months after the surgery, the patient received adjuvant chemotherapy (cisplatin/etoposide). After 14 months of follow-up, no local recurrence or distant metastasis was found.
UNASSIGNED: Ureteral collision carcinoma with SCNEC predominantly occurs in Asian individuals, is difficult to diagnose preoperatively and is highly invasive. The current management of ureteral collision carcinoma is a comprehensive treatment based on surgery.
UNASSIGNED: A 64-year-old male patient presented with a history of 1 month of gross haematuria and 3 months of left flank pain. CT urography revealed a soft tissue mass in the upper ureter, which was slightly enhanced on contrast-enhanced CT. Nephroureterectomy was performed after the patient was diagnosed with a tumour in the left ureter. Microscopy and immunohistochemical examination confirmed the mass to be a SCNEC collision with SCC. Two months after the surgery, the patient received adjuvant chemotherapy (cisplatin/etoposide). After 14 months of follow-up, no local recurrence or distant metastasis was found.
UNASSIGNED: Ureteral collision carcinoma with SCNEC predominantly occurs in Asian individuals, is difficult to diagnose preoperatively and is highly invasive. The current management of ureteral collision carcinoma is a comprehensive treatment based on surgery.
摘要：
■输尿管小细胞神经内分泌癌（SCNEC）是一种罕见的肿瘤，占所有输尿管肿瘤的不到0.5%。SCNEC肿瘤具有高度侵袭性，患者预后不良。输尿管SCNEC与其他病理类型的肿瘤碰撞极为罕见。在本文中,我们介绍了一例输尿管小细胞癌与鳞状细胞癌碰撞的病例，并回顾了有关临床病理特征的文献。因此肿瘤的治疗和预后。据我们所知,这是第2例输尿管SCNEC与SCC碰撞的病例.
■一名64岁男性患者，有1个月的肉眼血尿和3个月的左侧腹疼痛病史。CT尿路造影显示输尿管上段有软组织肿块,在对比增强CT上略有增强。在患者被诊断出患有左输尿管肿瘤后，进行了肾输尿管切除术。显微镜和免疫组织化学检查证实肿块是SCNEC与SCC碰撞。手术后两个月,患者接受辅助化疗(顺铂/依托泊苷).经过14个月的随访，未发现局部复发或远处转移。
■伴有SCNEC的输尿管碰撞癌主要发生在亚洲个体，术前难以诊断，并且具有很强的侵入性。目前输尿管碰撞癌的治疗是以手术为主的综合治疗。
■一名64岁男性患者，有1个月的肉眼血尿和3个月的左侧腹疼痛病史。CT尿路造影显示输尿管上段有软组织肿块,在对比增强CT上略有增强。在患者被诊断出患有左输尿管肿瘤后，进行了肾输尿管切除术。显微镜和免疫组织化学检查证实肿块是SCNEC与SCC碰撞。手术后两个月,患者接受辅助化疗(顺铂/依托泊苷).经过14个月的随访，未发现局部复发或远处转移。
■伴有SCNEC的输尿管碰撞癌主要发生在亚洲个体，术前难以诊断，并且具有很强的侵入性。目前输尿管碰撞癌的治疗是以手术为主的综合治疗。
