PDF(Pubmed)
Abstract：
Vitamin K antagonists (VKA) based oral anticoagulation, is widely used for the prevention and treatment of thromboembolic disease. The major complication of this therapy is bleeding, and sometimes it can occur in unsuspected areas. Spontaneous pectoral hematoma is one of the rare complications due to over anticoagulation by VKA therapy, with only a few cases reported in the literature. Concomitant use of this therapy with commonly used antibiotic, especially in the elderly with multiple comorbidities, can increase the risk of bleeding. Herein, we report a case of a 72-year-old woman under VKA for the treatment of atrial fibrillation, who presented with a spontaneous massive pectoral hematoma, while using antibiotic to treat a respiratory tract infection, who was successfully managed.
摘要：
维生素K拮抗剂（VKA）为基础的口服抗凝，广泛用于预防和治疗血栓栓塞性疾病。这种疗法的主要并发症是出血，有时它可能发生在不被怀疑的地区。自发性胸血肿是VKA治疗过度抗凝的罕见并发症之一,文献中只有少数病例报道。同时使用这种疗法与常用的抗生素，尤其是患有多种合并症的老年人，会增加出血的风险。在这里，我们报道了一例72岁女性接受VKA治疗的房颤患者，出现自发性巨大胸血肿，在使用抗生素治疗呼吸道感染时，谁被成功管理。
