Abstract:
Irritable bowel syndrome is one of the most common functional bowel disorders, and has a substantial impact on patients\' daily lives, as well as a big economic impact on society. It is characterised by abdominal pain, bloating and abdominal distention and altered bowel movements, with a predominance of diarrhoea, constipation, or alternation of these signs, which cannot be explained by a structural or biochemical abnormality. Its aetiopathogenesis and pathophysiological mechanism are unknown. The disease affects 5%-10% of healthy individuals at any given time and, in most people, has a relapsing-remitting course. This article reviews some of the main and most current evidence on its epidemiology, risk factors, pathophysiology, clinical manifestations, diagnostic approach, and therapeutic options, both dietary, pharmacological and psychotherapeutic.
摘要:
肠易激综合征是一种最常见的功能性肠道疾病,并对患者的日常生活产生重大影响,以及对社会的巨大经济影响。它的特点是腹痛,腹胀、腹胀和排便改变,腹泻占主导地位,便秘,或者这些迹象的交替,这不能用结构或生化异常来解释。其病因和病理生理机制尚不清楚。该疾病在任何给定时间影响5%-10%的健康个体,在大多数人身上,有复发缓解的过程。本文回顾了有关其流行病学的一些主要和最新证据,危险因素,病理生理学,临床表现,诊断方法,和治疗选择,两者都是饮食,药理学和心理治疗。